Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | CCR5 | P51681 | 9/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5758374 | 0.86 | CCR5 (0.60) | CCR5 | |
| SCHEMBL5758222 | 0.85 | OPRM1 (0.53) | SIGMAR1 | |
| SCHEMBL5754844 | 0.81 | KCNH2 (0.60) | KCNH2CCR5HTR2A | |
| SCHEMBL28602611 | 0.76 | KCNH2 (0.64) | KCNH2CCR5SIGMAR1 | |
| SCHEMBL6008659 | 0.73 | KCNH2 (0.53) | KCNH2CCR5HTR2ASIGMAR1S1PR5 | |
| SCHEMBL658329 | 0.72 | HDAC3 (0.49) | — | |
| SCHEMBL5758044 | 0.72 | KCNH2 (0.62) | KCNH2HTR2A | |
| SCHEMBL6009253 | 0.71 | KCNH2 (0.55) | KCNH2HTR2ASIGMAR1S1PR5CHRM2 | |
| SCHEMBL9647537 | 0.71 | HTR2A (0.72) | KCNH2HTR2ASIGMAR1 | |
| SCHEMBL8313722 | 0.71 | KCNH2 (0.71) | KCNH2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1401821-A4 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORP (KR) | 2006-05-31 | — | — | EP | claimed |
| EP-1401821-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK Corporation (KR) | 2004-03-31 | — | — | EP | claimed |
| WO-2002100848-A1 | NOVEL PHENYLALKYL DIAMINE AND AMIDE ANALOGS | SK CORPORATION (KR) | 2002-12-19 | — | — | WO | claimed |