Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | MEN1 | O00255 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.44 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 2/20 | 0.44 |
| ▸ | DRD3 | P35462 | 2/20 | 0.44 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754830 | 0.89 | RECQL (0.41) | RECQLMAPTMEN1KMT2ALMNA | |
| SCHEMBL5757154 | 0.85 | L3MBTL1 (0.54) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL5755890 | 0.80 | SLC2A1 (0.53) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5755893 | 0.80 | SLC2A1 (0.53) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5755880 | 0.80 | SLC2A1 (0.53) | MEN1KMT2ALMNAKDM4EALDH1A1 | |
| SCHEMBL5760090 | 0.79 | ABCB1 (0.47) | LMNAHTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL5777034 | 0.79 | HTR1A (0.49) | MAPTMEN1KMT2ALMNAHTR1A | |
| SCHEMBL6626086 | 0.78 | HTR1A (0.47) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL5754921 | 0.75 | MAPK1 (0.43) | MAPTMEN1KMT2ALMNATDP1 | |
| SCHEMBL9181593 | 0.73 | KMT2A (0.46) | RECQLMAPTMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343765-B1 | QUINOLINES AND NITROGENATED DERIVATIVES THEREOF SUBSTITUTED IN 4-POSITION BY A PIPERAZINE-CONTAINING MOIETY AND THEIR USE AS ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2006-11-22 | — | — | EP | claimed |