Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14350785 | 0.83 | MMP2 (0.40) | CCR2 | |
| SCHEMBL576440 | 0.83 | MMP2 (0.40) | CCR2 | |
| SCHEMBL5608693 | 0.81 | ALDH1A1 (0.35) | — | |
| SCHEMBL7034677 | 0.80 | POLB (0.40) | — | |
| SCHEMBL577270 | 0.79 | L3MBTL1 (0.35) | L3MBTL1 | |
| SCHEMBL296831 | 0.76 | CCR2 (0.49) | CCR2 | |
| SCHEMBL7038682 | 0.75 | SLC6A4 (0.44) | — | |
| SCHEMBL7033227 | 0.74 | LMNA (0.44) | L3MBTL1 | |
| SCHEMBL576582 | 0.73 | ALDH1A1 (0.39) | CCR2 | |
| SCHEMBL577347 | 0.73 | KMT2A (0.33) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030225282-A1 | Enantioselective process for preparing arylated lactones and derivatives | ZHANG TONY YANTAO (US) | 2003-12-04 | — | — | US | disclosed |
| EP-1286980-A2 | ENANTIOSELECTIVE PROCESS FOR PREPARING ARYLATED LACTONES AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 2003-03-05 | — | — | EP | disclosed |
| WO-2001072731-A2 | ENANTIOSELECTIVE PROCESS FOR PREPARING ARYLATED LACTONES AND DERIVATIVES | ELI LILLY AND COMPANY (US) | 2001-10-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030225282-A1 | Enantioselective process for preparing arylated lactones and derivatives | CYP51A1, AHR, LSS | CCR2 2855/4885L3MBTL1 2400/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.