Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.65 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.65 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11740596 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL10725884 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL4911879 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL4304828 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL10520655 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11737892 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11739399 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11739779 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11741978 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11740614 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588948-A | Soft biodegradable high-resilience polyurethane foaming plastic | ANHUI HUAIHUA CHEMICAL GROUP | 2014-02-19 | — | — | CN | claimed |
| CN-101426855-A | Composition for preparing a biodegradable polyurethane- based foam and a biodegradable polyurethane foam | PHB IND SA (BR) | 2009-05-06 | — | — | CN | claimed |
| CN-101389677-A | Composition for preparing a degradable polyol polyester, process for obtaining a polyol polyester, an elastomer, foams, paints and adhesives, and a degradable polyol polyester foam | PHB IND SA (BR) | 2009-03-18 | — | — | CN | claimed |
| EP-1673089-A2 | PHENYL-PIPERAZINE DERIVATIVES AS MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmaceuticals Incorporated (US) | 2006-06-28 | — | — | EP | claimed |
| WO-2005030188-A2 | PHENYL-PIPERAZINE DERIVATIVES AS MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-04-07 | — | — | WO | claimed |
| US-4057413-A | Methods and compositions for regulating plant growth using piperazine compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | claimed |
| WO-2024181373-A1 | METHOD FOR SELECTIVELY MODIFYING SUBSTRATE SURFACE, METHOD FOR PRODUCING SURFACE-TREATED SUBSTRATE, AND COMPOSITION | JSR株式会社 | 2024-09-06 | — | — | WO | disclosed |
| US-11312700-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | AERIE PHARMACEUTICALS, INC. (US) | 2022-04-26 | — | — | US | disclosed |
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | YALE UNIVERSITY (US) | 2021-04-06 | — | — | US | disclosed |
| US-20210002253-A1 | ARYL CYCLOPROPYL-AMINO-ISOQUINOLINYL AMIDE COMPOUNDS | ALCON INC. (CH) | 2021-01-07 | — | — | US | disclosed |
| US-20190276425-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | UNIV YALE (US) | 2019-09-12 | — | — | US | disclosed |
| CN-103588948-A | Soft biodegradable high-resilience polyurethane foaming plastic | ANHUI HUAIHUA CHEMICAL GROUP | 2014-02-19 | — | — | CN | disclosed |
| CN-102492109-A | Biodegradable high-resilience flexible polyurethane foam plastics and its preparation method | UNIV XI AN SCI & TECHNOLOGY | 2012-06-13 | — | — | CN | disclosed |
| CN-101426855-A | Composition for preparing a biodegradable polyurethane- based foam and a biodegradable polyurethane foam | PHB IND SA (BR) | 2009-05-06 | — | — | CN | disclosed |
| EP-1673089-A2 | PHENYL-PIPERAZINE DERIVATIVES AS MODULATORS OF MUSCARINIC RECEPTORS | Vertex Pharmaceuticals Incorporated (US) | 2006-06-28 | — | — | EP | disclosed |
| WO-2005030188-A2 | PHENYL-PIPERAZINE DERIVATIVES AS MODULATORS OF MUSCARINIC RECEPTORS | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2005-04-07 | — | — | WO | disclosed |
| US-4057413-A | Methods and compositions for regulating plant growth using piperazine compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10968198-B2 | Biaryltriazole inhibitors of macrophage migration inhibitory factor | MIF, MMP12, CSF1R | GNAI3 112/4885GNAO1 1401/4885GNAI1 262/4885 |
| US-20210002253-A1 | ARYL CYCLOPROPYL-AMINO-ISOQUINOLINYL AMIDE COMPOUNDS | UACA, HRAS, MYLK | GNAI3 83/4885GNAO1 537/4885GNAI1 71/4885 |
| US-11312700-B2 | Aryl cyclopropyl-amino-isoquinolinyl amide compounds | UACA, HRAS, MYLK | GNAI3 83/4885GNAO1 537/4885GNAI1 71/4885 |
| US-20190276425-A1 | BIARYLTRIAZOLE INHIBITORS OF MACROPHAGE MIGRATION INHIBITORY FACTOR | MIF, MMP12, CSF1R | GNAI3 112/4885GNAO1 1401/4885GNAI1 262/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.