Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNAI3 | P08754 | 6/20 | 0.65 |
| ▸ | GNAO1 | P09471 | 6/20 | 0.65 |
| ▸ | GNAI1 | P63096 | 6/20 | 0.65 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | GUSB | P08236 | 2/20 | 0.47 |
| ▸ | EBP | Q15125 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11739779 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL10520655 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11741978 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL10725884 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11737892 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL5770286 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL4911879 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11740614 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11740596 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E | |
| SCHEMBL11739399 | 1.00 | GNAI3 (0.65) | GNAI3GNAO1GNAI1PAOXKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-1168602-A | — | — | None | — | — | JP | disclosed |
| WO-2024181373-A1 | METHOD FOR SELECTIVELY MODIFYING SUBSTRATE SURFACE, METHOD FOR PRODUCING SURFACE-TREATED SUBSTRATE, AND COMPOSITION | JSR株式会社 | 2024-09-06 | — | — | WO | disclosed |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| US-11578079-B2 | SUMO inhibitor compounds and uses thereof | CITY OF HOPE (US) | 2023-02-14 | — | — | US | disclosed |
| EP-4116302-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | Tianjin Jikun Medical Technology Co., Ltd. (CN) | 2023-01-11 | — | — | EP | disclosed |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | Ryvu Therapeutics S.A. (PL) | 2022-12-22 | — | — | US | disclosed |
| WO-2022127261-A1 | COMPOUND AND PREPARATION METHOD THEREOF AND APPLICATION THEREOF IN PREPARATION OF THERAPEUTIC ANTI-CANCER DRUG | 天津济坤医药科技有限公司 | 2022-06-23 | — | — | WO | disclosed |
| US-20220128562-A1 | BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF | UNIVERSITY OF KANSAS | 2022-04-28 | — | — | US | disclosed |
| US-11180474-B2 | Dimethoxyphenyl substituted indole compounds as TLR7, TLR8 or TLR9 inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2021-11-23 | — | — | US | disclosed |
| US-11174251-B2 | Compositions and methods for inhibition of the JAK pathway | RIGEL PHARMACEUTICALS, INC. (US) | 2021-11-16 | — | — | US | disclosed |
| US-8207157-B2 | agents result in masking attractive odors from insects that normally would be receptive to the attractants by producing anosmia or hyposmia in the insects; ticks, mites, cockroaches and mosquitoes | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2012-06-26 | — | — | US | disclosed |
| US-8207157-B2 | agents result in masking attractive odors from insects that normally would be receptive to the attractants by producing anosmia or hyposmia in the insects; ticks, mites, cockroaches and mosquitoes | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2012-06-26 | — | — | US | disclosed |
| EP-2099455-A1 | METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | The United States of America, as represented by the Secretary ofd Agrigulture (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2008-08-07 | — | — | US | disclosed |
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2008-08-07 | — | — | US | disclosed |
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE | 2008-08-07 | — | — | US | disclosed |
| WO-2008083038-A1 | METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2008-07-10 | — | — | WO | disclosed |
| WO-2008083038-A1 | METHODS AND COMPOSITIONS FOR REPELLING ARTHROPODS | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE (US) | 2008-07-10 | — | — | WO | disclosed |
| JP-H01168602-A | REPELLENT AGAINST SANITARY INSECT PEST | NICHIBAI BOEKI KK | 1989-07-04 | — | — | JP | disclosed |
| US-4057413-A | Methods and compositions for regulating plant growth using piperazine compounds | BAYER AKTIENGESELLSCHAFT (DT) | 1977-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11578079-B2 | SUMO inhibitor compounds and uses thereof | SUMO1, SUMO2, UBE2I | GNAI3 2687/4885GNAO1 3704/4885GNAI1 2094/4885 |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | PLTP, LNPEP, PLIN3 | GNAI3 1283/4885GNAO1 2211/4885GNAI1 1986/4885 |
| US-11174251-B2 | Compositions and methods for inhibition of the JAK pathway | JAK3, JAK2, JAK1 | GNAI3 397/4885GNAO1 2822/4885GNAI1 751/4885 |
| US-20080188456-A1 | Methods and Compositions For Repelling Arthropods | HRH4, CHRM5, OPRM1 | GNAI3 3553/4885GNAO1 2004/4885GNAI1 3396/4885 |
| US-20220402898-A1 | MODULATORS OF STIMULATOR OF INTERFERON GENES (STING) | STING1, IRF3, CGAS | GNAI3 118/4885GNAO1 114/4885GNAI1 60/4885 |
| US-11180474-B2 | Dimethoxyphenyl substituted indole compounds as TLR7, TLR8 or TLR9 inhibitors | TLR9, TLR7, TLR8 | GNAI3 283/4885GNAO1 527/4885GNAI1 178/4885 |
| US-20220128562-A1 | BIOMARKERS PREDICTIVE OF CANCER CELL RESPONSE TO ML329 OR A DERIVATIVE THEREOF | NQO1, KEAP1, NFE2L2 | GNAI3 813/4885GNAO1 2620/4885GNAI1 1394/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.