Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 8/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 7/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | KLK7 | P49862 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5768940 | 0.94 | ABCB1 (0.51) | ABCB1MAPTCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL5772347 | 0.91 | POLB (0.50) | ALDH1A1MEN1KMT2ATP53POLB | |
| SCHEMBL5772968 | 0.77 | POLB (0.52) | MAPTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5771774 | 0.77 | ALOX15 (0.47) | CYP3A4ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2070701 | 0.72 | ALDH1A1 (0.69) | ABCB1MAPTCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL5898903 | 0.72 | MAPT (0.57) | ABCB1MAPTCYP3A4ALDH1A1MAPK1 | |
| SCHEMBL4745653 | 0.72 | PIN1 (0.73) | MAPTCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL5310100 | 0.69 | XDH (0.50) | MAPTCYP3A4ALDH1A1MEN1KMT2A | |
| SCHEMBL28750722 | 0.69 | ALOX15 (0.60) | MAPTCYP3A4ALDH1A1MAPK1MEN1 | |
| SCHEMBL5139795 | 0.69 | ALOX15 (0.75) | ALDH1A1MEN1KMT2ATP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2005027900-A1 | BENZOFURAN DERIVATIVES | GALILEO PHARMACEUTICALS, INC. (US) | 2005-03-31 | — | — | WO | disclosed |