SCHEMBL57725

SCHEMBL57725

CCOC(OCC)n1ccnc1

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 8/20 0.40
NFKB1 P19838 1/20 0.39
QPCT Q16769 1/20 0.39
HSD17B10 Q99714 1/20 0.39
QPCTL Q9NXS2 1/20 0.39
CYP17A1 P05093 9/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28798620 0.90 CYP19A1 (0.40) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL2648843 0.87 CYP19A1 (0.35) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL7739960 0.83 CYP19A1 (0.40) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL16700622 0.82 CYP17A1 (0.41) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL9791620 0.82 CYP19A1 (0.39) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL7268446 0.80 CYP19A1 (0.38) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL7712264 0.77 CYP19A1 (0.39) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL1406898 0.76 CYP19A1 (0.47) CYP19A1NFKB1QPCTHSD17B10QPCTL
SCHEMBL28269017 0.73 TBXAS1 (0.45) CYP19A1CYP17A1
Methane SCHEMBL27640067 0.72 CYP17A1 (0.44) CYP19A1CYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 198 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US claimed
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY 2020-06-04 US claimed
WO-2018213821-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME THE GEORGE WASHINGTON UNIVERSITY (US) 2018-11-22 WO claimed
US-10125226-B2 Scale-up process of bifunctionalized triblock copolymers with secondary and tertiary amines, with application in dewatering and desalting of heavy crude oils INSTITUTO MEXICANO DEL PETROLEO (MX) 2018-11-13 US claimed
US-20140364566-A1 SCALE-UP PROCESS OF BIFUNCTIONALIZED TRIBLOCK COPOLYMERS WITH SECONDARY AND TERTIARY AMINES, WITH APPLICATION IN DEWATERING AND DESALTING OF HEAVY CRUDE OILS INSTITUTO MEXICANO DEL PETROLEO (MX) 2014-12-11 US claimed
CN-102775437-A Carbon dioxide transition metal complex, preparation method and application thereof UNIV NORTHWESTERN 2012-11-14 CN claimed
US-7960440-B2 Highly dispersible carbon nanospheres in an organic solvent and methods for making same HEADWATERS TECHNOLOGY INNOVATION LLC (US) 2011-06-14 US claimed
WO-2009085365-A1 HIGHLY DISPERSIBLE CARBON NANOSPHERES IN AN ORGANIC SOLVENT AND METHODS FOR MAKING SAME HEADWATERS TECHNOLOGY INNOVATION, LLC (US) 2009-07-09 WO claimed
US-20090093554-A1 HIGHLY DISPERSIBLE CARBON NANOSPHERES IN AN ORGANIC SOLVENT AND METHODS FOR MAKING SAME HEADWATERS TECHNOLOGY INNOVATION, LLC (US) 2009-04-09 US claimed
US-12496282-B2 Hepatitis B antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2025-12-16 US disclosed
US-12391673-B2 LANCL ligands NIMMUNE BIOPHARMA, INC. (US) 2025-08-19 US disclosed
CN-115403608-B Spirofluorene silicon compound and electroluminescent application thereof 上海天马微电子有限公司 2025-05-02 CN disclosed
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same THE GEORGE WASHINGTON UNIVERSITY (US) 2025-01-14 US disclosed
US-20240366538-A1 Hepatitis B Antiviral Agents ENANTA PHARM INC (US) 2024-11-07 US disclosed
CN-86108027-A Prepare new 2,2 '-method of Lian-1H-imidazoles 1987-10-07 CN disclosed
EP-0229922-A2 Novel 2,2'-BI-1H-imidazoles MERRELL DOW PHARMACEUTICALS INC. (US) 1987-07-29 EP disclosed
EP-0222598-A2 Dihydropyridine anti-ischaemic and antihypertensive agents Pfizer Limited (GB) 1987-05-20 EP disclosed
US-4469865-A INHIBITORS OF THROMBOXANE SYNTHETASE KISSEI PHARMACEUTICAL CO., LTD. (JP) 1984-09-04 US disclosed
US-4461905-A THROMBOXANE SYNTHETASE INHIBITOR INTERMEDIATE ONO PHARMACEUTICAL CO., LTD. (JP) 1984-07-24 US disclosed
EP-0076140-A2 1,3-Disubstituted imidazoles and a process for their production Kissei Pharmaceutical Co. Ltd. (JP) 1983-04-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12194448-B2 Catalysts for the transformation of carbon dioxide and glycerol to formic acid and lactic acid and methods of making the same MLX, LDHA, CA2 CYP19A1 2426/4885NFKB1 4761/4885QPCT 1318/4885
US-12391673-B2 LANCL ligands LANCL2, LANCL1, ACSL1 CYP19A1 4071/4885NFKB1 1309/4885QPCT 1734/4885
US-20240366538-A1 Hepatitis B Antiviral Agents HAVCR2, PYGL, SLC10A1 CYP19A1 1465/4885NFKB1 392/4885QPCT 499/4885
US-20200171474-A1 CATALYSTS FOR THE TRANSFORMATION OF CARBON DIOXIDE AND GLYCEROL TO FORMIC ACID AND LACTIC ACID AND METHODS OF MAKING THE SAME MLX, LDHA, CA2 CYP19A1 2426/4885NFKB1 4761/4885QPCT 1318/4885
US-12496282-B2 Hepatitis B antiviral agents HAVCR2, PYGL, SLC10A1 CYP19A1 1465/4885NFKB1 392/4885QPCT 499/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.