SCHEMBL5772648

SCHEMBL5772648

C=C[Si](C=C)(C=C)c1cccc([Si](C=C)(C=C)C=C)c1

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29214114 0.84 NFE2L2 (0.41)
SCHEMBL17973724 0.84 TP53 (0.48) TP53TDP1
SCHEMBL1674781 0.80 ALDH1A1 (0.41)
SCHEMBL29214167 0.79 TSHR (0.44)
SCHEMBL8083285 0.76
SCHEMBL5774391 0.76 NR1H2 (0.32)
SCHEMBL5772639 0.74 NR1H2 (0.42) TP53TDP1
SCHEMBL5773688 0.74 TP53 (0.33) TP53TDP1
SCHEMBL18806234 0.72 TGM2 (0.44)
SCHEMBL3321240 0.70 TSHR (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060134336-A1 Novel polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR CORPORATION (JP) 2006-06-22 US disclosed
EP-1661934-A1 Polycarbosilane and method of producing the same, film-forming composition, and film and method of forming the same JSR Corporation (JP) 2006-05-31 EP disclosed