Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRNP | P04156 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.54 |
| ▸ | MEN1 | O00255 | 6/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | METAP2 | P50579 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | AURKA | O14965 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21828961 | 0.88 | KMT2A (0.60) | PRNPKMT2AMEN1ATMKDM4E | |
| SCHEMBL6135290 | 0.87 | ATM (0.61) | KMT2AMEN1ATMKDM4EALDH1A1 | |
| SCHEMBL148106 | 0.81 | PRNP (0.76) | PRNPKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL634722 | 0.80 | ATM (0.55) | KMT2AATMKDM4EALDH1A1GAA | |
| SCHEMBL7424428 | 0.80 | ALDH1A1 (0.46) | PRNPKMT2AMEN1ATMKDM4E | |
| SCHEMBL31090849 | 0.80 | ALDH1A1 (0.46) | PRNPKMT2AMEN1ATMKDM4E | |
| SCHEMBL6913620 | 0.79 | PRNP (0.73) | PRNPKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL6913244 | 0.79 | PRNP (0.73) | PRNPKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10405412 | 0.79 | PRNP (0.58) | PRNPKMT2AMEN1ALDH1A1AHR | |
| SCHEMBL6913860 | 0.79 | PRNP (0.73) | PRNPKMT2AMEN1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112945912-B | High-brightness large-Stokes-shift wash-free lipid-droplet fluorescent probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2023-02-21 | — | — | CN | claimed |
| CN-112945912-A | High-brightness large-Stokes-shift wash-free lipid-droplet fluorescent probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | claimed |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | PEPTIDREAM INC (JP) | 2024-12-05 | — | — | US | disclosed |
| CN-112945912-B | High-brightness large-Stokes-shift wash-free lipid-droplet fluorescent probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2023-02-21 | — | — | CN | disclosed |
| CN-112945912-A | High-brightness large-Stokes-shift wash-free lipid-droplet fluorescent probe and synthetic method and application thereof | 中国科学院大连化学物理研究所 | 2021-06-11 | — | — | CN | disclosed |
| EP-3275867-B1 | PYRIDO-FUSED BICYCLIC COMPOUNDS AS URAT1 INHIBITORS FOR TREATING HYPERURICEMIA | SHANGHAI YINGLI PHARM CO LTD (CN) | 2020-06-10 | — | — | EP | disclosed |
| US-20180072678-A1 | CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | SHANGHAI YINGLI PHARMACEUTICAL CO., LTD. (CN) | 2018-03-15 | — | — | US | disclosed |
| WO-2016150255-A1 | CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | 上海璎黎药业有限公司 | 2016-09-29 | — | — | WO | disclosed |
| EP-1020446-B1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO LTD (JP) | 2006-03-15 | — | — | EP | disclosed |
| US-6300331-B1 | DRUGS AS ANTITUMOR AGENTS OR ANTICARCINOGENIC AGENTS | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2001-10-09 | — | — | US | disclosed |
| EP-1020446-A1 | NAPHTHALIMIDOBENZAMIDE DERIVATIVES | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180072678-A1 | CONDENSED RING DERIVATIVE, AND PREPARATION METHOD, INTERMEDIATE, PHARMACEUTICAL COMPOSITION AND USE THEREOF | URB2, UGP2, NLRP3 | PRNP 3128/4885KMT2A 821/4885MEN1 2678/4885 |
| US-20240400499-A1 | NOVEL AMINO ACID DERIVATIVES | BCAT1, BCAT2, PELP1 | PRNP 735/4885KMT2A 3415/4885MEN1 4354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.