Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | MMP2 | P08253 | 3/20 | 0.40 |
| ▸ | MMP8 | P22894 | 3/20 | 0.40 |
| ▸ | MMP12 | P39900 | 3/20 | 0.40 |
| ▸ | MMP13 | P45452 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 3/20 | 0.40 |
| ▸ | MMP16 | P51512 | 3/20 | 0.40 |
| ▸ | MMP9 | P14780 | 2/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoromethanesulfonic Acid SCHEMBL5774894 | 0.78 | KDM4E (0.49) | MMP2MMP8MMP12MMP13MMP14 | |
| Trifluoromethanesulfonic Acid SCHEMBL1592826 | 0.73 | PKM (0.47) | MMP2MMP8MMP13MMP9MMP1 | |
| Trifluoromethanesulfonic Acid SCHEMBL361656 | 0.71 | KCNH2 (0.46) | MMP2MMP12MMP9KEAP1HTT | |
| SCHEMBL12375158 | 0.69 | NPC1 (0.42) | HTTNPSR1 | |
| Trifluoromethanesulfonic Acid SCHEMBL5828338 | 0.68 | PKM (0.47) | MMP2MMP8MMP13MMP9MMP1 | |
| SCHEMBL16527104 | 0.67 | HSD17B10 (0.59) | HSD17B10NPSR1POLBL3MBTL1KDM4E | |
| Trifluoromethanesulfonic Acid SCHEMBL5851777 | 0.66 | ACHE (0.39) | HTT | |
| Trifluoromethanesulfonic Acid SCHEMBL30295478 | 0.66 | ACHE (0.39) | HTT | |
| Trifluoromethanesulfonic Acid SCHEMBL34468116 | 0.66 | CA1 (0.40) | HSD17B10KDM4E | |
| Trifluoroacetic Acid SCHEMBL3167314 | 0.65 | NQO2 (0.40) | HSD17B10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732865-A1 | FLUORIDATION METHOD | GE Healthcare Limited (GB) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097713-A1 | FLUORIDATION METHOD | GE HEALTHCARE LIMITED (GB) | 2005-10-20 | — | — | WO | disclosed |