Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 18/20 | 0.43 |
| ▸ | NR3C2 | P08235 | 11/20 | 0.43 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260079 | 0.87 | PDK1 (0.38) | NR3C1NR3C2 | |
| SCHEMBL3540058 | 0.85 | ERN1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL27760976 | 0.81 | NR3C1 (0.35) | NR3C1NR3C2PGR | |
| SCHEMBL5277847 | 0.78 | NR3C1 (0.38) | NR3C1NR3C2PGR | |
| SCHEMBL3751137 | 0.78 | CTSS (0.32) | — | |
| SCHEMBL3745087 | 0.78 | CTSS (0.32) | — | |
| SCHEMBL28762151 | 0.78 | AKR1C3 (0.36) | — | |
| SCHEMBL1261086 | 0.78 | CTSS (0.32) | — | |
| SCHEMBL4629304 | 0.76 | NR3C1 (0.64) | NR3C1NR3C2PGR | |
| SCHEMBL1260203 | 0.74 | L3MBTL1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1638945-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | Schering Aktiengesellschaft (DE) | 2006-03-29 | — | — | EP | disclosed |
| WO-2005003098-A1 | HETEROCYCLICALLY SUBSTITUTED PENTANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, AND USE THEREOF AS ANTI-INFLAMMATORY AGENTS | SCHERING AKTIENGESELLSCHAFT (DE) | 2005-01-13 | — | — | WO | disclosed |