Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 6/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.35 |
| ▸ | PGR | P06401 | 2/20 | 0.35 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.33 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1260079 | 0.89 | PDK1 (0.38) | NR3C1NR3C2LPAR1L3MBTL1HPGD | |
| SCHEMBL3540058 | 0.86 | ERN1 (0.35) | NR3C1NR3C2PGRL3MBTL1HPGD | |
| SCHEMBL27782520 | 0.86 | P2RX7 (0.34) | NR3C1NR3C2PGRCYP19A1L3MBTL1 | |
| SCHEMBL1261398 | 0.83 | HSD11B1 (0.33) | NR3C1NR3C2PGRSMN1; SMN2KMT2A | |
| SCHEMBL5774836 | 0.81 | NR3C1 (0.43) | NR3C1NR3C2PGR | |
| SCHEMBL3745087 | 0.79 | CTSS (0.32) | MEN1CYP3A4KMT2A | |
| SCHEMBL1261086 | 0.79 | CTSS (0.32) | MEN1CYP3A4KMT2A | |
| SCHEMBL3751137 | 0.79 | CTSS (0.32) | MEN1CYP3A4KMT2A | |
| SCHEMBL27650704 | 0.77 | NR3C1 (0.45) | NR3C1NR3C2PGRCYP19A1 | |
| SCHEMBL1260203 | 0.76 | L3MBTL1 (0.42) | L3MBTL1HPGDSMN1; SMN2NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101553472-A | Tetrahydronaphthaline derivatives, methods for the production and use thereof as anti-inflammatory agents | BAYER SCHERING PHARMA AG (DE) | 2009-10-07 | — | — | CN | disclosed |