Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.43 |
| ▸ | TUBB | P07437 | 2/20 | 0.43 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.43 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.43 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.43 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.43 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.43 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9264435 | 0.85 | KDM4E (0.49) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9573791 | 0.82 | TUBB4A (0.46) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL9242488 | 0.81 | ALDH1A1 (0.48) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL5776615 | 0.81 | KDM4E (0.45) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL3949912 | 0.79 | GSK3B (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8549182 | 0.77 | GABRA1 (0.47) | KDM4EALDH1A1MAPTMEN1RAB9A | |
| SCHEMBL8553897 | 0.77 | KDM4E (0.51) | KDM4EALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL43369 | 0.77 | KDM4E (0.63) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1122036 | 0.76 | GAA (0.46) | KDM4EALDH1A1MAPTGSK3BLMNA | |
| SCHEMBL2327495 | 0.75 | GABRA1 (0.50) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639573-A1 | Benzocondensed five membered heterocycles, process of their preparation, their use as drug, as diagnostic means and pharmaceuticals containing it | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-02-22 | — | — | EP | disclosed |