Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MGLL | Q99685 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | PIM1 | P11309 | 1/20 | 0.34 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5775682 | 0.96 | MGLL (0.41) | MAOBMGLLFFAR1FFAR4CYP1A2 | |
| SCHEMBL5778231 | 0.92 | MAOB (0.36) | MAOBFFAR1FFAR4PIM1PIM2 | |
| SCHEMBL5777269 | 0.87 | MAOB (0.41) | MAOBMGLLFFAR1FFAR4PIM1 | |
| SCHEMBL5774430 | 0.85 | MAOB (0.40) | MAOBMGLLFFAR1FFAR4L3MBTL1 | |
| SCHEMBL5775678 | 0.83 | MGLL (0.43) | MAOBMGLLFFAR1FFAR4PIM1 | |
| SCHEMBL5779454 | 0.82 | ROCK2 (0.45) | MAOBMGLLENPP2POLBHDAC1 | |
| SCHEMBL6164962 | 0.82 | MAOB (0.43) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL5774651 | 0.79 | MAOB (0.37) | MAOBFFAR1FFAR4PIM1PIM2 | |
| SCHEMBL6163345 | 0.78 | CA12 (0.46) | MAOBMGLLFFAR1FFAR4ENPP2 | |
| SCHEMBL6164397 | 0.78 | PTPN1 (0.50) | MAOBMGLLFFAR1FFAR4ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1368345-B1 | ALKOXYCARBONYLAMINO HETEROARYL CARBOXYLIC ACID DERIVATIVES AS IP ANTAGONISTS | HOFFMANN LA ROCHE (CH) | 2006-03-22 | — | — | EP | claimed |