Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | SLC6A15 | Q9H2J7 | 1/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6034220 | 0.77 | GRM5 (0.41) | P2RX4BCHEGRM5GRM1GPR119 | |
| SCHEMBL6033980 | 0.67 | ALDH1A1 (0.42) | P2RX4BCHEGRM5GRM1MAPT | |
| SCHEMBL16342946 | 0.65 | P2RX4 (0.46) | P2RX4BCHELMNASCN9ASCN10A | |
| SCHEMBL6110762 | 0.65 | P2RX4 (0.46) | P2RX4BCHELMNASCN9ASCN10A | |
| SCHEMBL1383152 | 0.64 | — | — | |
| SCHEMBL4064728 | 0.64 | MAPT (0.40) | P2RX4BCHEGRM5GRM1GPR119 | |
| SCHEMBL13757380 | 0.61 | DPP8 (0.56) | SLC6A15 | |
| SCHEMBL27770600 | 0.60 | L3MBTL1 (0.34) | MAPTLMNAL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL28423158 | 0.60 | MAPT (0.46) | MAPTLMNAL3MBTL1MEN1ALDH1A1 | |
| SCHEMBL5771784 | 0.60 | TSHR (0.39) | P2RX4BCHEALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732933-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005097805-A1 | COMPOUNDS AND METHODS FOR TREATING DYSLIPIDEMIA | ELI LILLY AND COMPANY (US) | 2005-10-20 | — | — | WO | disclosed |