Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IMPDH2 | P12268 | 11/20 | 0.42 |
| ▸ | IMPDH1 | P20839 | 5/20 | 0.42 |
| ▸ | AAK1 | Q2M2I8 | 8/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5777067 | 0.81 | IMPDH2 (0.56) | IMPDH2IMPDH1AAK1MAP4K4 | |
| SCHEMBL5779035 | 0.79 | IMPDH2 (0.60) | IMPDH2IMPDH1AAK1MAP4K4 | |
| SCHEMBL14518599 | 0.78 | IMPDH2 (0.68) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL5778422 | 0.74 | RAB9A (0.49) | IMPDH2 | |
| SCHEMBL5776770 | 0.73 | PKM (0.58) | IMPDH2IMPDH1AAK1MAP4K4 | |
| Hydrochloric Acid SCHEMBL5776713 | 0.71 | PKM (0.56) | IMPDH2IMPDH1AAK1MAP4K4 | |
| SCHEMBL13151143 | 0.71 | MAP4K4 (0.68) | IMPDH2MAP4K4 | |
| SCHEMBL14364371 | 0.71 | LMNA (0.47) | IMPDH2IMPDH1AAK1MAP4K4 | |
| SCHEMBL5774602 | 0.70 | AAK1 (0.45) | IMPDH2IMPDH1AAK1 | |
| SCHEMBL5776255 | 0.69 | CYP11B1 (0.47) | AAK1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-12-07 | — | — | US | disclosed |
| EP-1612204-A1 | HYDRAZONE DERIVATIVE | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 2006-01-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276433-A1 | Hydrazone derivative | APP, PRNP, HTT | IMPDH2 4694/4885IMPDH1 4461/4885AAK1 1161/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.