Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.30 |
| ▸ | SSTR2 | P30874 | 2/20 | 0.30 |
| ▸ | SSTR4 | P31391 | 2/20 | 0.30 |
| ▸ | SSTR3 | P32745 | 2/20 | 0.30 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.30 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5178946 | 0.90 | MTNR1A (0.36) | RHEBMTNR1AMTNR1BHRH3LOXL2 | |
| SCHEMBL2562389 | 0.82 | RHEB (0.36) | RHEBMTNR1AMTNR1BLOXL2 | |
| SCHEMBL1661108 | 0.81 | ALDH1A1 (0.39) | MTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL5778097 | 0.80 | DAO (0.39) | MTNR1AMTNR1BHRH3LOXL2DAO | |
| SCHEMBL694595 | 0.79 | ADORA1 (0.39) | MTNR1AMTNR1BHRH3LOXL2KDM4E | |
| SCHEMBL1662293 | 0.79 | CYP1A2 (0.41) | MTNR1AMTNR1BKDM4E | |
| SCHEMBL31278346 | 0.77 | LOXL2 (0.56) | RHEBMTNR1AMTNR1BHRH3LOXL2 | |
| SCHEMBL2071314 | 0.77 | LOXL2 (0.56) | RHEBMTNR1AMTNR1BHRH3LOXL2 | |
| SCHEMBL188218 | 0.75 | GAA (0.35) | MTNR1AMTNR1BHRH3LOXL2 | |
| SCHEMBL189125 | 0.75 | LOXL2 (0.37) | MTNR1AMTNR1BLOXL2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660427-A4 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORP (JP) | 2006-12-20 | — | — | EP | disclosed |
| EP-1660427-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | Asahi Kasei Pharma Corporation (JP) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005016862-A1 | SUBSTITUTED ARYLALKANOIC ACID DERIVATIVE AND USE THEREOF | ASAHI KASEI PHARMA CORPORATION (JP) | 2005-02-24 | — | — | WO | disclosed |