Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4F2 | P78329 | 2/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.40 |
| ▸ | S1PR4 | O95977 | 3/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.40 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.39 |
| ▸ | GHSR | Q92847 | 2/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27617207 | 0.76 | GAA (0.46) | MEN1KMT2A | |
| SCHEMBL9551532 | 0.75 | GAA (0.45) | MEN1KMT2A | |
| SCHEMBL5779280 | 0.73 | MGLL (0.44) | CYP4F2CYP4A11S1PR1S1PR4S1PR5 | |
| SCHEMBL15946021 | 0.71 | ALDH1A1 (0.49) | CYP4F2CYP4A11S1PR1S1PR4S1PR5 | |
| SCHEMBL6041291 | 0.71 | MEN1 (0.57) | S1PR1S1PR4S1PR3CA2MEN1 | |
| SCHEMBL9204156 | 0.71 | CYP4F2 (0.52) | CYP4F2CYP4A11S1PR1S1PR4S1PR5 | |
| SCHEMBL8867307 | 0.71 | NR3C1 (0.50) | CYP4F2CYP4A11TBXA2RHTR6PTPN1 | |
| SCHEMBL2176833 | 0.70 | CYP4F2 (0.56) | CYP4F2CYP4A11TBXA2RCA2MGLL | |
| SCHEMBL10235701 | 0.69 | LPL (0.57) | CYP4F2CYP4A11SPHK1LPLLIPG | |
| SCHEMBL3033916 | 0.69 | LPL (0.62) | CYP4F2CYP4A11MEN1KMT2ALPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646659-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | Neurochem (International) Limited (CH) | 2006-04-19 | — | — | EP | disclosed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |