Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.41 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.37 |
| ▸ | GHSR | Q92847 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28801780 | 0.82 | HTR7 (0.51) | MGLLALDH1A1HTR7CA2PTPN1 | |
| SCHEMBL15946021 | 0.81 | ALDH1A1 (0.49) | CYP4F2CYP4A11ALDH1A1KCNH3S1PR4 | |
| SCHEMBL2151090 | 0.81 | HTR6 (0.47) | CYP4F2CYP4A11ALDH1A1KCNH3HTR7 | |
| SCHEMBL11475109 | 0.76 | HTR7 (0.49) | MGLLALDH1A1HTR7KMT2AMEN1 | |
| SCHEMBL10795105 | 0.76 | MEN1 (0.46) | ALDH1A1CA2KMT2AMEN1LMNA | |
| SCHEMBL2151141 | 0.75 | ALDH1A1 (0.42) | CYP4F2CYP4A11ALDH1A1KCNH3HTR7 | |
| SCHEMBL11515443 | 0.75 | DDX3X (0.45) | ALDH1A1CA2HTR6KMT2AMEN1 | |
| SCHEMBL1897682 | 0.75 | MAPT (0.61) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL2150855 | 0.74 | TDP1 (0.51) | ALDH1A1KMT2AMEN1MAPTHTT | |
| SCHEMBL11410042 | 0.74 | S1PR1 (0.53) | KCNH3S1PR4S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646659-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | Neurochem (International) Limited (CH) | 2006-04-19 | — | — | EP | disclosed |
| WO-2004113391-A2 | IMPROVED PHARMACEUTICAL DRUG CANDIDATES AND METHODS FOR PREPARATION THEREOF | NEUROCHEM (INTERNATIONAL) LIMITED (CH) | 2004-12-29 | — | — | WO | disclosed |