Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 2/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1639465 | 0.96 | PIN1 (0.49) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL32688297 | 0.91 | MAOB (0.44) | PIN1PTGS2L3MBTL1TSHRCYP1A2 | |
| SCHEMBL16086043 | 0.90 | PIN1 (0.43) | PIN1ALOX5PTGS2L3MBTL1CYP1A2 | |
| SCHEMBL11009131 | 0.89 | TSHR (0.52) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL17066149 | 0.88 | L3MBTL1 (0.45) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL22686879 | 0.84 | PIN1 (0.45) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL28776503 | 0.83 | PIN1 (0.49) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL8670167 | 0.82 | PIN1 (0.48) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL16253511 | 0.80 | L3MBTL1 (0.51) | PIN1ALOX5PTGS2L3MBTL1TSHR | |
| SCHEMBL17563554 | 0.80 | MAOB (0.47) | PTGS2L3MBTL1LMNAPTGS1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116813710-A | Preparation method of carfilzomib | 重庆药友制药有限责任公司 | 2023-09-29 | — | — | CN | claimed |
| CN-116768972-A | Preparation method of carfilzomib intermediate | 重庆药友制药有限责任公司 | 2023-09-19 | — | — | CN | claimed |
| US-8946475-B2 | Processes for preparing a polymeric compound | CELLCEUTIX CORPORATION (US) | 2015-02-03 | — | — | US | claimed |
| EP-1912951-B1 | PREPARATION OF 1,7` -DIMETHYL-2 `-PROPYL-2,5` -BI-1H-BENZIMIDAZOLE | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-01-06 | — | — | EP | claimed |
| US-7608722-B2 | Preparation of 1,7,′-dimethyl-2′-propyl-2,5′-bi-1H-benzimidazole | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-27 | — | — | US | claimed |
| EP-1912951-A1 | PREPARATION OF 1,7` -DIMETHYL-2 `-PROPYL-2,5` -BI-1H-BENZIMIDAZOLE | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-04-23 | — | — | EP | claimed |
| US-20070037986-A1 | reacting N-methyl-o-phenylenediamine with 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid, coupling and cyclization is achieved using 1,3,5-triazine ( 2-chloro-4,6-dimethoxy-1,3,5-triazine) and tertiary amine ( morpholine, N-methyl-) | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-02-15 | — | — | US | claimed |
| WO-2007009967-A1 | PREPARATION OF 1,7′-DIMETHYL-2′-PROPYL-2,5′-BI-1H-BENZIMIDAZOLE | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-01-25 | — | — | WO | claimed |
| US-20250067734-A1 | Fluorescent Cellulose Particles | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-02-27 | — | — | US | disclosed |
| CN-116813710-B | Preparation method of carfilzomib | 重庆药友制药有限责任公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-118119848-A | Fluorescent cellulose particles | 旭化成株式会社 | 2024-05-31 | — | — | CN | disclosed |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | INNOVATION PHARMACEUTICALS INC. (US) | 2023-10-05 | — | — | US | disclosed |
| CN-116813710-A | Preparation method of carfilzomib | 重庆药友制药有限责任公司 | 2023-09-29 | — | — | CN | disclosed |
| CN-116768972-A | Preparation method of carfilzomib intermediate | 重庆药友制药有限责任公司 | 2023-09-19 | — | — | CN | disclosed |
| US-7608722-B2 | Preparation of 1,7,′-dimethyl-2′-propyl-2,5′-bi-1H-benzimidazole | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-10-27 | — | — | US | disclosed |
| EP-1951691-A1 | PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS | Italvelluti S.p.A. (IT) | 2008-08-06 | — | — | EP | disclosed |
| EP-1912951-A1 | PREPARATION OF 1,7` -DIMETHYL-2 `-PROPYL-2,5` -BI-1H-BENZIMIDAZOLE | Boehringer Ingelheim Pharma GmbH & Co. KG (DE) | 2008-04-23 | — | — | EP | disclosed |
| WO-2007051496-A1 | PROCESS FOR THE PREPARATION OF N-TRIAZINYLAMMONIUM SALTS | ITALVELLUTI S.P.A. (IT) | 2007-05-10 | — | — | WO | disclosed |
| US-20070037986-A1 | reacting N-methyl-o-phenylenediamine with 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid, coupling and cyclization is achieved using 1,3,5-triazine ( 2-chloro-4,6-dimethoxy-1,3,5-triazine) and tertiary amine ( morpholine, N-methyl-) | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-02-15 | — | — | US | disclosed |
| WO-2007009967-A1 | PREPARATION OF 1,7′-DIMETHYL-2′-PROPYL-2,5′-BI-1H-BENZIMIDAZOLE | BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG (DE) | 2007-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070037986-A1 | reacting N-methyl-o-phenylenediamine with 2-propyl-4-methyl-1H-benzimidazole-6-carboxylic acid, coupling and cyclization is achieved using 1,3,5-triazine ( 2-chloro-4,6-dimethoxy-1,3,5-triazine) and tertiary amine ( morpholine, N-methyl-) | PNMT, PAM, PAH | PIN1 1448/4885ALOX5 1464/4885PTGS2 1105/4885 |
| US-20230310435-A1 | HOST DEFENSE PROTEIN (HDP) MIMETICS FOR PROPHYLAXIS AND/OR TREATMENT OF INFLAMMATORY DISEASES OF THE GASTROINTESTINAL TRACT | FABP2, HMGB1, MASP2 | PIN1 3129/4885ALOX5 1447/4885PTGS2 647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.