Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 8/20 | 0.47 |
| ▸ | CNR1 | P21554 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.40 |
| ▸ | GABRD | O14764 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28779811 | 0.84 | PTPN11 (0.48) | CNR2PPARARARB | |
| SCHEMBL28779825 | 0.82 | PTPN11 (0.46) | CNR2PPARARARB | |
| SCHEMBL15391024 | 0.79 | PPARA (0.40) | CNR2CNR1PPARAMAPTALDH1A1 | |
| SCHEMBL7043252 | 0.77 | ALDH1A1 (0.40) | CNR2CNR1PPARAMAPTALDH1A1 | |
| SCHEMBL3313891 | 0.76 | PPARA (0.40) | CNR2CNR1PPARAPPARGKAT8 | |
| SCHEMBL4327627 | 0.75 | PPARA (0.54) | PPARAMAPTALDH1A1CYP3A4GAA | |
| SCHEMBL9068637 | 0.75 | PPARA (0.54) | PPARAMAPTALDH1A1CYP3A4GAA | |
| SCHEMBL9068780 | 0.75 | PPARA (0.54) | PPARAMAPTALDH1A1CYP3A4GAA | |
| SCHEMBL6112733 | 0.75 | PPARA (0.54) | PPARAMAPTALDH1A1CYP3A4GAA | |
| SCHEMBL460892 | 0.74 | KDM4E (0.57) | MAPTALDH1A1CYP3A4GAAESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2492301-B1 | NOVEL CO-MODIFIED ORGANOPOLYSILOXANE | DOW TORAY CO LTD (JP) | 2023-03-29 | — | — | EP | disclosed |
| EP-3438159-B1 | ORGANOPOLYSILOXANE, COSMETIC MATERIAL, AND METHOD FOR PRODUCING ORGANOPOLYSILOXANE | SHINETSU CHEMICAL CO (JP) | 2021-03-31 | — | — | EP | disclosed |
| US-10662294-B2 | Organopolysiloxane, cosmetics, and method for manufacturing organopolysiloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2020-05-26 | — | — | US | disclosed |
| EP-2921518-B1 | ORGANOPOLYSILOXANE HAVING AMIDE GROUP, AND COSMETIC MATERIAL CONTAINING SAME | SHINETSU CHEMICAL CO (JP) | 2019-06-19 | — | — | EP | disclosed |
| US-20190077920-A1 | ORGANOPOLYSILOXANE, COSMETICS, AND METHOD FOR MANUFACTURING ORGANOPOLYSILOXANE | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2019-03-14 | — | — | US | disclosed |
| EP-3438159-A1 | ORGANOPOLYSILOXANE, COSMETIC MATERIAL, AND METHOD FOR PRODUCING ORGANOPOLYSILOXANE | Shin-Etsu Chemical Co., Ltd. (JP) | 2019-02-06 | — | — | EP | disclosed |
| US-9890252-B2 | Silicone compound and cosmetic containing thereof | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2018-02-13 | — | — | US | disclosed |
| EP-3168255-B1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHINETSU CHEMICAL CO (JP) | 2018-01-31 | — | — | EP | disclosed |
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-05-18 | — | — | US | disclosed |
| EP-3168255-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | Shin-Etsu Chemical Co., Ltd. (JP) | 2017-05-17 | — | — | EP | disclosed |
| US-20060222615-A1 | Cosmetic preparation | KANEBO COSMETICS INC. (JP) | 2006-10-05 | — | — | US | disclosed |
| EP-1496080-B1 | Alternating copolymer of organopolysiloxane with glycerol derivative and a cosmetic comprising the same | SHINETSU CHEMICAL CO (JP) | 2006-04-26 | — | — | EP | disclosed |
| US-6984390-B2 | Silicone compound and cosmetic preparation | SHIN-ETSU CHEMICAL CO. LTD. (JP) | 2006-01-10 | — | — | US | disclosed |
| EP-1607081-A1 | COSMETIC PREPARATION | Kanebo Cosmetics, Inc. (JP) | 2005-12-21 | — | — | EP | disclosed |
| US-20050008600-A1 | Alternating copolymer of organopolysiloxane with grycerol derivative and a cosmetic comprising the same | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1496080-A1 | Alternating copolymer of organopolysiloxane with glycerol derivative and a cosmetic comprising the same | Shin-Etsu Chemical Company, Ltd. (JP) | 2005-01-12 | — | — | EP | disclosed |
| EP-1481660-A1 | Cosmetic | Shin-Etsu Chemical Co., Ltd. (JP) | 2004-12-01 | — | — | EP | disclosed |
| EP-1291376-A1 | SILICONE POLYMER, SILICONE COMPOSITION, AND COSMETIC PREPARATION CONTAINING THE SAME | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-1291377-A1 | SILICONE COMPOUND AND COSMETIC PREPARATION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-1213006-A1 | COSMETICS | KANEBO, LTD. (JP) | 2002-06-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170137574-A1 | NOVEL SILICONE COMPOUND AND COSMETIC CONTAINING THEREOF | CCND2, MRGPRX1, MRGPRX2 | CNR2 638/4885CNR1 909/4885PPARA 4286/4885 |
| US-20190077920-A1 | ORGANOPOLYSILOXANE, COSMETICS, AND METHOD FOR MANUFACTURING ORGANOPOLYSILOXANE | PIEZO1, H1-0, TRPA1 | CNR2 1506/4885CNR1 966/4885PPARA 3198/4885 |
| US-20050008600-A1 | Alternating copolymer of organopolysiloxane with grycerol derivative and a cosmetic comprising the same | MGLL, DAGLA, AGL | CNR2 3984/4885CNR1 3379/4885PPARA 838/4885 |
| US-10662294-B2 | Organopolysiloxane, cosmetics, and method for manufacturing organopolysiloxane | PIEZO1, H1-0, TRPA1 | CNR2 1506/4885CNR1 966/4885PPARA 3198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.