Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.33 |
| ▸ | FASN | P49327 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5786541 | 0.91 | HTR6 (0.42) | HTR6PKMALDH1A1KDM4ETP53 | |
| SCHEMBL5697885 | 0.88 | LMNA (0.39) | HTR6PKMALDH1A1KDM4ELMNA | |
| SCHEMBL5784055 | 0.87 | GBA1 (0.40) | HTR6PKMKDM4E | |
| SCHEMBL5697915 | 0.87 | HTR6 (0.37) | HTR6PKMALDH1A1KDM4ELMNA | |
| SCHEMBL5786579 | 0.87 | MEN1 (0.40) | HTR6ALDH1A1LMNAL3MBTL1POLB | |
| SCHEMBL5441438 | 0.86 | ALDH1A1 (0.43) | HTR6PKMALDH1A1KDM4ELMNA | |
| SCHEMBL5783278 | 0.85 | PKM (0.42) | HTR6PKMALDH1A1KDM4ELMNA | |
| SCHEMBL5781747 | 0.85 | CHRM1 (0.36) | PKMALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL6051263 | 0.85 | HTR6 (0.43) | HTR6PKMALDH1A1TP53FASN | |
| SCHEMBL5782809 | 0.84 | PKM (0.40) | HTR6PKMALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1648886-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-04-26 | — | — | EP | disclosed |
| WO-2005014589-A1 | BENZOXAZINONE-DERIVED SULFONAMIDE COMPOUNDS, THEIR PREPARATION AND USE AS MEDICAMENTS | LABORATORIOS DEL DR. ESTEVE S.A. (DE) | 2005-02-17 | — | — | WO | disclosed |