SCHEMBL578568

SCHEMBL578568

CCCC(C)(CO)COC(=O)NCC(=O)OCC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.44
HSD17B10 Q99714 2/20 0.44
TSHR P16473 3/20 0.43
RAB9A P51151 3/20 0.43
CYP3A4 P08684 1/20 0.43
NFKB1 P19838 1/20 0.43
ADRA1A P35348 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
GAA P10253 3/20 0.41
MGAM O43451 1/20 0.37
SI P14410 1/20 0.37
MGAM2 Q2M2H8 1/20 0.37
SMN1; SMN2 Q16637 3/20 0.35
PPID Q08752 2/20 0.35
ALDH1A1 P00352 4/20 0.35
MAPT P10636 1/20 0.35
NPC1 O15118 2/20 0.35
HPGD P15428 1/20 0.34
PPIB P23284 1/20 0.34
PPIA P62937 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10041806 0.86 LMNA (0.45) LMNAHSD17B10TSHRRAB9ACYP3A4
SCHEMBL10041808 0.85 LMNA (0.45) LMNAHSD17B10TSHRRAB9ACYP3A4
SCHEMBL10042249 0.83 TSHR (0.67) LMNAHSD17B10TSHRRAB9ACYP3A4
SCHEMBL10041811 0.81 LMNA (0.41) LMNAHSD17B10TSHRRAB9ACYP3A4
Carbamic Acid SCHEMBL578833 0.79 LMNA (0.44) LMNAHSD17B10TSHRRAB9ACYP3A4
Carbamic Acid SCHEMBL578480 0.78 LMNA (0.42) LMNAHSD17B10TSHRRAB9ACYP3A4
SCHEMBL2482646 0.76 GAA (0.59) HSD17B10TSHRRAB9AGAAMGAM
SCHEMBL578604 0.75 LMNA (0.73) LMNAHSD17B10TSHRRAB9ACYP3A4
SCHEMBL5244425 0.75 SMN1; SMN2 (0.42) LMNAHSD17B10TSHRRAB9ACYP3A4
Hydrochloric Acid SCHEMBL27762950 0.74 GAA (0.57) HSD17B10TSHRRAB9AGAAMGAM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2418492-B1 Immunoreagent for meprobamate RANDOX LABORATORIES LTD (GB) 2018-10-10 EP disclosed
US-20120040378-A1 Meprobromate Immunoassay RANDOX LABORATORIES LIMITED (GB) 2012-02-16 US disclosed
US-20120040378-A1 Meprobromate Immunoassay RANDOX LABORATORIES LIMITED (GB) 2012-02-16 US disclosed
EP-2418492-A1 Meprobamate immunoassay Randox Laboratories Ltd. (GB) 2012-02-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120040378-A1 Meprobromate Immunoassay MEP1B, CES2, MEP1A LMNA 4619/4885HSD17B10 449/4885TSHR 740/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.