Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 9/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 9/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5783540 | 0.90 | MAPT (0.35) | ITGB3ITGA2BMEN1KMT2ANPC1 | |
| SCHEMBL5783451 | 0.88 | TPSAB1 (0.37) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5783767 | 0.87 | RAB9A (0.41) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5784888 | 0.86 | HRH3 (0.33) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5814482 | 0.85 | L3MBTL1 (0.35) | ITGB3ITGA2BMAPT | |
| SCHEMBL5787633 | 0.80 | MAPT (0.33) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL5787025 | 0.79 | ALDH1A1 (0.34) | MEN1KMT2ANPC1MAPTRAB9A | |
| SCHEMBL5782142 | 0.79 | MAPT (0.36) | ITGB3ITGA2BMAPT | |
| SCHEMBL5788613 | 0.79 | NPC1 (0.41) | NPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL5781728 | 0.78 | POLB (0.36) | NPC1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | claimed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | claimed |