Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | ITGB3 | P05106 | 4/20 | 0.32 |
| ▸ | ITGA2B | P08514 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | EDNRA | P25101 | 2/20 | 0.30 |
| ▸ | IDH1 | O75874 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5784707 | 0.92 | HPGD (0.38) | L3MBTL1MAPTKDM4EGLAHPGD | |
| SCHEMBL5784542 | 0.89 | HPGD (0.39) | MAPTKDM4EPOLBGLAHPGD | |
| SCHEMBL5787100 | 0.85 | ITGB3 (0.41) | MAPTITGB3ITGA2B | |
| SCHEMBL5782451 | 0.85 | HPGD (0.46) | MAPTKDM4EGLAHPGD | |
| SCHEMBL5787816 | 0.84 | HPGD (0.36) | L3MBTL1MAPTKDM4EGLAHPGD | |
| SCHEMBL5785742 | 0.84 | HPGD (0.36) | L3MBTL1MAPTKDM4EPOLBTSHR | |
| SCHEMBL5786901 | 0.82 | HPGD (0.35) | L3MBTL1MAPTKDM4EPOLBGLA | |
| SCHEMBL5784006 | 0.80 | HPGD (0.36) | L3MBTL1MAPTKDM4EPOLBGLA | |
| SCHEMBL5783451 | 0.80 | TPSAB1 (0.37) | L3MBTL1MAPTKDM4EPOLBHPGD | |
| SCHEMBL5785104 | 0.79 | RAB9A (0.36) | MAPTKDM4ETSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1677783-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | Nicholas Piramal India Limited (IN) | 2006-07-12 | — | — | EP | disclosed |
| WO-2005035495-A2 | FIBRINOGEN RECEPTOR ANTAGONISTS AND THEIR USE | NICHOLAS PIRAMAL INDIA LIMITED (IN) | 2005-04-21 | — | — | WO | disclosed |