SCHEMBL5788697

SCHEMBL5788697

CC(C)(C)O[C@@H](Cc1ccccc1)[C@H](O)C(Cl)N=C=O

nearest known ligand 0.34

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CTSS P25774 2/20 0.34
CTSL P07711 1/20 0.34
CTSB P07858 1/20 0.34
CTSK P43235 1/20 0.34
ATM Q13315 1/20 0.33
KLK5 Q9Y337 2/20 0.32
TRPA1 O75762 2/20 0.31
CYP1A2 P05177 1/20 0.31
CTRB1 P17538 2/20 0.31
HPGD P15428 1/20 0.31
LAP3 P28838 1/20 0.31
ITGA4 P13612 1/20 0.31
ITGB7 P26010 1/20 0.31
ACE P12821 1/20 0.31
SRR Q9GZT4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7808946 0.79 CYP1A2 (0.39) CTSSCTSLCTSBCTSKATM
SCHEMBL7821232 0.79 CYP1A2 (0.39) CTSSCTSLCTSBCTSKATM
SCHEMBL8932578 0.78 CTSS (0.42) CTSSCTSKACESRR
SCHEMBL5792810 0.74 SRR (0.39) CTSSCTSLCTSBCTSKSRR
SCHEMBL12483826 0.68 ITGA4 (0.48) CTSSCTSLCTSBCTSKATM
SCHEMBL10441236 0.68 ITGA4 (0.48) CTSSCTSLCTSBCTSKATM
SCHEMBL9120328 0.67 TRPA1 (0.44) ATMTRPA1CYP1A2LAP3SRR
SCHEMBL9118343 0.67 TAAR1 (0.42) ATMTRPA1CYP1A2
SCHEMBL28997356 0.67 CYP1A2 (0.41) CYP1A2LAP3
SCHEMBL21056125 0.64 SLC6A2 (0.48) CYP1A2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006016116-A1 PROCESS FOR ASYMMETRIC CATALYTIC HYDROGENATION PHOENIX CHEMICALS LIMITED (GB) 2006-02-16 WO disclosed