Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792304 | 0.92 | MAPT (0.46) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL8482518 | 0.75 | PDK1 (0.49) | KMT2AALDH1A1KDM4EPDK1 | |
| SCHEMBL8482514 | 0.72 | PDK1 (0.46) | KMT2AGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL6954360 | 0.72 | MEN1 (0.44) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL11923509 | 0.68 | ADRA1A (0.35) | — | |
| SCHEMBL23932135 | 0.68 | KMT2A (0.43) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL183877 | 0.68 | KMT2A (0.43) | MAPTMEN1KMT2ALMNAGAA | |
| SCHEMBL2877889 | 0.68 | MAPT (0.47) | MAPTMEN1KMT2AGAANPSR1 | |
| SCHEMBL1134463 | 0.68 | ALDH1A1 (0.53) | MAPTMEN1KMT2AGAAALDH1A1 | |
| SCHEMBL21831956 | 0.67 | KDM4E (0.45) | MAPTMEN1KMT2ALMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006005726-A2 | HETEROCYCLIC COMPOUNDS | SPEEDEL EXPERIMENTA AG (CH) | 2006-01-19 | — | — | WO | disclosed |