Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 10/20 | 0.44 |
| ▸ | KCNQ3 | O43525 | 4/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 4/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSS | P25774 | 2/20 | 0.38 |
| ▸ | CTSC | P53634 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | GPR4 | P46093 | 1/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5791503 | 0.89 | CTSK (0.47) | CTSKCTSBCTSSCTSCCTSL | |
| SCHEMBL8271448 | 0.87 | CTSK (0.46) | CTSKCTSLFGFR4AR | |
| SCHEMBL8268844 | 0.83 | CTSK (0.45) | CTSKCTSBCTSSCTSCCTSL | |
| SCHEMBL8270467 | 0.83 | CTSK (0.48) | CTSKCTSBCTSSCTSCCTSL | |
| SCHEMBL5791966 | 0.82 | CTSK (0.45) | CTSKCTSSCTSLFGFR4 | |
| SCHEMBL8271447 | 0.82 | CTSK (0.43) | CTSKFGFR4 | |
| SCHEMBL5792274 | 0.82 | CTSK (0.43) | CTSKCTSSMCHR1 | |
| SCHEMBL8270779 | 0.79 | CTSK (0.40) | CTSKCTSBCTSSCTSCCTSL | |
| SCHEMBL8270485 | 0.78 | CTSK (0.37) | CTSKCTSBCTSSCTSCCTSL | |
| SCHEMBL5791397 | 0.78 | CTSK (0.48) | CTSKCTSBCTSSCTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |