Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 8/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.36 |
| ▸ | PPARD | Q03181 | 3/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.35 |
| ▸ | CDK9 | P50750 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7505970 | 0.86 | PTGS2 (0.51) | PTGS2PTGS1NR3C1 | |
| SCHEMBL5791783 | 0.75 | KDM1A (0.36) | PTGS2PTGS1FFAR1PPARDKDM1A | |
| SCHEMBL8776835 | 0.73 | PTGS2 (0.45) | PTGS2PTGS1NR3C1 | |
| SCHEMBL9484876 | 0.72 | L3MBTL1 (0.53) | PTGS2PTGS1FFAR1PPARDKDM1A | |
| SCHEMBL6930665 | 0.72 | PTGS2 (0.36) | PTGS2PTGS1 | |
| SCHEMBL9119397 | 0.71 | EGFR (0.38) | PTGS2PTGS1L3MBTL1NR3C1 | |
| SCHEMBL9119298 | 0.69 | PTGS2 (0.38) | PTGS2PTGS1 | |
| SCHEMBL9118873 | 0.68 | PTGS2 (0.42) | PTGS2PTGS1 | |
| SCHEMBL9118988 | 0.68 | PTGS2 (0.45) | PTGS2PTGS1 | |
| SCHEMBL16572511 | 0.67 | FGFR1 (0.49) | PTGS2PTGS1FFAR1PPARDKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1660500-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005014598-A1 | SUBSTITUTED IMIDAZOPYRIMIDINES FOR THE PREVENTION AND TREATMENT OF CANCER | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2005-02-17 | — | — | WO | disclosed |