Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 9/20 | 0.38 |
| ▸ | CTSS | P25774 | 4/20 | 0.38 |
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | CTSB | P07858 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8270730 | 0.94 | CTSK (0.42) | CTSKCTSSCTSLCTSBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5791900 | 0.92 | CTSK (0.44) | CTSKCTSSCTSLCTSBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5793822 | 0.89 | MAPK8 (0.35) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5794599 | 0.87 | CTSK (0.38) | CTSKCTSSCTSLCTSB | |
| SCHEMBL5790864 | 0.86 | HTT (0.39) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL8271456 | 0.86 | CTSK (0.47) | CTSKCTSSCTSLCTSBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5794677 | 0.85 | CTSK (0.39) | CTSKCTSSCTSLCTSBKMT2A | |
| Trifluoroacetic Acid SCHEMBL5791925 | 0.85 | CTSK (0.38) | CTSKCTSSCTSLCTSBKMT2A | |
| SCHEMBL5804787 | 0.85 | HPGD (0.41) | CTSKCTSSCTSLCTSBSMN1; SMN2 | |
| SCHEMBL5792191 | 0.85 | WNT3A (0.38) | CTSKCTSSCTSLCTSBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | claimed |
| WO-2006027211-A1 | 2,4-SUBSTITUTED PYRIMIDINES AS CYSTEINE PROTEASE INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-03-16 | — | — | WO | disclosed |