Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | GRK6 | P43250 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 3/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BTK | Q06187 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | CASP6 | P55212 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL402013 | 0.86 | BCAT2 (0.56) | BCAT2KEAP1NFE2L2PARP1PDK2 | |
| SCHEMBL1512043 | 0.82 | MMP2 (0.47) | BCAT2KEAP1NFE2L2BRD4PARP1 | |
| SCHEMBL5608858 | 0.80 | BCAT2 (0.61) | BCAT2KEAP1NFE2L2PARP1PDK2 | |
| SCHEMBL11218560 | 0.80 | ALDH1A1 (0.50) | BCAT2KEAP1NFE2L2BRD4PARP1 | |
| SCHEMBL998313 | 0.80 | MMP2 (0.48) | BCAT2KEAP1NFE2L2GRK6PARP1 | |
| SCHEMBL3804575 | 0.79 | ALDH1A1 (0.50) | BCAT2KEAP1NFE2L2GRK6BRD4 | |
| SCHEMBL5791255 | 0.78 | GRK6 (0.48) | BCAT2KEAP1NFE2L2GRK6BRD4 | |
| Hydrochloric Acid SCHEMBL631451 | 0.78 | MMP2 (0.47) | BCAT2KEAP1NFE2L2GRK6PARP1 | |
| SCHEMBL14990637 | 0.78 | MMP2 (0.53) | MMP2ALDH1A1KDM4EMAPTHSD17B10 | |
| SCHEMBL466296 | 0.77 | KDM4E (0.54) | BCAT2KEAP1NFE2L2PARP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006009696-A2 | ANTICOAGULANT CONTRAST MEDIA | HEMATROPE PHARMACEUTICALS INC (US) | 2006-01-26 | — | — | WO | disclosed |
| US-20050281746-A1 | Anticoagulant contrast media | HEMATROPE PHARMACEUTICALS, INC. | 2005-12-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050281746-A1 | Anticoagulant contrast media | SERPINC1, F2, TFPI | BCAT2 3446/4885KEAP1 2277/4885NFE2L2 4197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.