Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.42 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5789524 | 0.94 | P2RX3 (0.40) | PKMGAAKDM4ELMNASTAT3 | |
| SCHEMBL5792442 | 0.92 | CACNA1G (0.42) | KDM4EACHEMEN1KMT2ACHRM4 | |
| SCHEMBL8277406 | 0.91 | PKM (0.47) | PKMGAAKDM4ELMNAACHE | |
| SCHEMBL8275457 | 0.91 | PKM (0.47) | PKMGAAKDM4ELMNAACHE | |
| SCHEMBL5789493 | 0.91 | PKM (0.49) | PKMGAAKDM4ELMNAACHE | |
| SCHEMBL5791743 | 0.87 | PKM (0.43) | PKMGAAKDM4ELMNANPC1 | |
| SCHEMBL5792966 | 0.87 | ACHE (0.41) | PKMACHECHRM4 | |
| SCHEMBL5791157 | 0.87 | HIF1A (0.42) | PKMCHRM2 | |
| SCHEMBL5792428 | 0.85 | PRKAA2 (0.45) | KDM4ELMNAACHEMEN1KMT2A | |
| SCHEMBL5791554 | 0.84 | MAOB (0.44) | GAAKDM4ELMNACHRM2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006002956-A1 | PIPERIDINE DERIVATIVES AND THEIR USE AS GLYCINE TRANSPORTER INHIBITORS | GLAXO GROUP LIMITED (GB) | 2006-01-12 | — | — | WO | claimed |