Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | DUT | P33316 | 5/20 | 0.35 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064655 | 0.81 | PKM (0.51) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL8656960 | 0.79 | PKM (0.45) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL5792152 | 0.77 | CRBN (0.42) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL11581000 | 0.76 | ALDH1A1 (0.43) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL41240 | 0.76 | PKM (0.42) | PKMCRBNDUTL3MBTL1 | |
| SCHEMBL24709729 | 0.75 | DUT (0.41) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL4278691 | 0.75 | PKM (0.38) | PKMCRBNALDH1A1LMNADUT | |
| SCHEMBL1673256 | 0.75 | KMT2A (0.42) | PKMALDH1A1LMNADUTL3MBTL1 | |
| SCHEMBL11546247 | 0.74 | DUT (0.41) | PKMCRBNDUTMAPT | |
| SCHEMBL20529215 | 0.73 | ALDH1A1 (0.44) | PKMCRBNALDH1A1LMNADUT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1064263-A2 | NONNUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE FOR THE TREATMENT OF HIV-INFECTION | Parker Hughes Institute (US) | 2001-01-03 | — | — | EP | claimed |
| WO-1999047501-A2 | NONNUCLEOSIDE INHIBITORS OF REVERSE TRANSCRIPTASE FOR THE TREATMENT OF HIV-INFECTION | PARKER HUGHES INSTITUTE (US) | 1999-09-23 | — | — | WO | claimed |