Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | CACNA1I | Q9P0X4 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5792117 | 0.83 | GABRA5 (0.43) | KCNH2CNR2MCHR1 | |
| SCHEMBL5792816 | 0.78 | CCR2 (0.47) | KMT2AKCNH2CACNA1HCYP2D6ALDH1A1 | |
| SCHEMBL5791107 | 0.72 | KMT2A (0.47) | KMT2ALMNAKCNH2CACNA1HCYP2D6 | |
| SCHEMBL27684178 | 0.67 | CNR1 (0.72) | KMT2ACNR1CNR2MEN1 | |
| SCHEMBL5791461 | 0.66 | KMT2A (0.49) | KMT2ALMNAALDH1A1MEN1KDM4E | |
| SCHEMBL5793901 | 0.66 | SLC6A3 (0.45) | KCNH2CNR2 | |
| SCHEMBL8363043 | 0.65 | BCHE (0.75) | KMT2ALMNAGAACYP2D6ALDH1A1 | |
| SCHEMBL10196664 | 0.65 | MMP13 (0.61) | KMT2ALMNAGAAKCNH2CACNA1H | |
| SCHEMBL2070654 | 0.64 | ALDH1A1 (0.51) | KMT2ALMNAGAAALDH1A1MEN1 | |
| SCHEMBL5790711 | 0.64 | ACKR3 (0.54) | KMT2ACNR1CNR2ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006012577-A2 | QUINAZOLINONE DERIVATIVES USEFUL FOR THE REGULATION OF GLUCOSE HOMEOSTASIS AND FOOD INTAKE | BAYER PHARMACEUTICALS CORPORATION (US) | 2006-02-02 | — | — | WO | disclosed |