SCHEMBL589624

SCHEMBL589624

Nc1ccc(Cl)cc1C(=O)NCC1CC1

nearest known ligand 0.54

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 9/20 0.54
CHRM2 P08172 2/20 0.52
CHRM4 P08173 2/20 0.52
CHRM3 P20309 2/20 0.52
CNR2 P34972 2/20 0.52
CHRM5 P08912 1/20 0.52
CCR2 P41597 2/20 0.50
FADS1 O60427 1/20 0.50
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
CNR1 P21554 1/20 0.48
POLB P06746 1/20 0.48
HTR4 Q13639 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27684193 0.93 NPC1 (0.57) CHRM1CHRM2CHRM4CHRM3CNR2
SCHEMBL15534964 0.89 HTR4 (0.47) CHRM1CHRM2CHRM4CHRM3CNR2
SCHEMBL15534965 0.89 HTR4 (0.47) CHRM1CHRM2CHRM4CHRM3CNR2
SCHEMBL4845927 0.83 CHRM1 (0.58) CHRM1CHRM2CHRM4CHRM3CHRM5
SCHEMBL17434345 0.80 ALDH1A1 (0.57) CCR2POLB
SCHEMBL14734915 0.79 CNR2 (0.49) CHRM1CHRM2CHRM4CHRM3CNR2
SCHEMBL6205964 0.78 CCR2 (0.81) CCR2HTR4
SCHEMBL11689255 0.78 NOS2 (0.63) CCR2FADS1POLB
SCHEMBL2154639 0.78 ALDH1A1 (0.56) CHRM1CHRM2CHRM4CHRM3NPC1
SCHEMBL14686258 0.78 CNR2 (0.60) CHRM1CNR2NPC1RAB9APOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103204811-B Process for production of anthranilamide compound ISHIHARA SANGYO KAISHA 2015-02-04 CN disclosed
EP-2093223-B1 PROCESS AND INTERMEDIATES FOR PRODUCTION OF AN ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA (JP) 2013-08-21 EP disclosed
CN-103204811-A Process For Production Of Anthranilamide Compound ISHIHARA SANGYO KAISHA 2013-07-17 CN disclosed
CN-101558056-B Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA 2013-05-01 CN disclosed
US-8115006-B2 Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2012-02-14 US disclosed
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA ,LTD. (JP) 2010-03-11 US disclosed
CN-101558056-A Process for producing anthranilamide compound ISHIHARA SANGYO KAISHA (JP) 2009-10-14 CN disclosed
EP-2093223-A1 PROCESS FOR PRODUCTION OF ANTHRANILAMIDE COMPOUND ISHIHARA SANGYO KAISHA, LTD. (JP) 2009-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063293-A1 PROCESS FOR PRODUCING ANTHRANILAMIDE COMPOUND NAAA, AAAS, AADAC CHRM1 2756/4885CHRM2 3112/4885CHRM4 3863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.