Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.78 |
| ▸ | MAPT | P10636 | 9/20 | 0.78 |
| ▸ | RAB9A | P51151 | 9/20 | 0.78 |
| ▸ | NPC1 | O15118 | 8/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.78 |
| ▸ | MEN1 | O00255 | 6/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.75 |
| ▸ | CASP1 | P29466 | 2/20 | 0.75 |
| ▸ | TSHR | P16473 | 1/20 | 0.75 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 6/20 | 0.71 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.71 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | FLT3 | P36888 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15731000 | 0.78 | ALDH1A1 (0.76) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL7003934 | 0.76 | ALDH1A1 (0.70) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL8290734 | 0.75 | HPGD (1.00) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL5453296 | 0.75 | FLT3 (1.00) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL7004914 | 0.75 | NPC1 (0.61) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL8288650 | 0.74 | ALDH1A1 (0.68) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL6996786 | 0.74 | FLT3 (0.70) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL6997315 | 0.73 | ALDH1A1 (0.60) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL5460090 | 0.72 | ALDH1A1 (0.74) | ALDH1A1MAPTRAB9ANPC1KMT2A | |
| SCHEMBL7902809 | 0.72 | GRIN2C (1.00) | ALDH1A1MAPTRAB9ANPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006026619-A3 | INHIBITION OF VIRUSES USING RNASE H INHIBITORS | US HEALTH (US) | 2006-05-04 | — | — | WO | disclosed |
| WO-2006026619-A2 | INHIBITION OF VIRUSES USING RNASE H INHIBITORS | GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2006-03-09 | — | — | WO | disclosed |