Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 1/20 | 0.53 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3131049 | 0.86 | P2RX7 (0.56) | P2RX7RIPK1RXFP1HPGDALDH1A1 | |
| SCHEMBL16709645 | 0.83 | P2RX7 (0.53) | P2RX7RIPK1RXFP1HPGDALDH1A1 | |
| SCHEMBL5797618 | 0.80 | P2RX7 (0.53) | P2RX7HPGDRAB9A | |
| SCHEMBL5794698 | 0.78 | ALDH1A1 (0.50) | P2RX7RIPK1RXFP1HPGDALDH1A1 | |
| SCHEMBL12680205 | 0.77 | RPS6KA1 (0.49) | P2RX7RIPK1RXFP1HPGDALDH1A1 | |
| SCHEMBL5705865 | 0.74 | MCL1 (0.49) | P2RX7HPGDALDH1A1MAPTGAA | |
| SCHEMBL5795605 | 0.73 | P2RX7 (0.51) | P2RX7ALDH1A1SMN1; SMN2RAB9AMEN1 | |
| SCHEMBL5854222 | 0.72 | GABRA1 (0.46) | P2RX7RIPK1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL9102212 | 0.72 | P2RX7 (0.45) | P2RX7RIPK1ALDH1A1SMN1; SMN2RAB9A | |
| SCHEMBL868842 | 0.72 | CXCL8 (0.53) | P2RX7SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |