Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5968206 | 0.94 | ALDH1A1 (0.54) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL4204174 | 0.76 | ALDH1A1 (0.72) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL6407491 | 0.69 | PKM (0.60) | KMT2ASMN1; SMN2LMNAALDH1A1TDP1 | |
| SCHEMBL24164778 | 0.67 | HTT (0.59) | KMT2ASMN1; SMN2MEN1LMNAALDH1A1 | |
| SCHEMBL6405832 | 0.66 | ALDH1A1 (1.00) | KMT2ASMN1; SMN2MEN1ALDH1A1TDP1 | |
| SCHEMBL17112348 | 0.66 | FFAR1 (0.71) | SMN1; SMN2ALDH1A1KDM4ERAB9APOLB | |
| SCHEMBL6405274 | 0.66 | GAA (0.74) | KMT2AMEN1LMNAALDH1A1GAA | |
| SCHEMBL19334382 | 0.65 | KMT2A (0.67) | KMT2AMEN1ALDH1A1TDP1TSHR | |
| SCHEMBL19926288 | 0.65 | ALDH1A1 (0.65) | SMN1; SMN2ALDH1A1RAB9APOLBNPC1 | |
| SCHEMBL28359974 | 0.64 | HTT (0.56) | KMT2ASMN1; SMN2LMNAALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1615637-A1 | PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES | NOVO NORDISK A/S (DK) | 2006-01-18 | — | — | EP | disclosed |
| WO-2004089367-A1 | PHARMACEUTICAL USE OF SUBSTITUTED 1,2,4-TRIAZOLES | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | disclosed |