Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5794958 | 0.89 | PPARG (0.42) | RAB9AMCL1SMN1; SMN2TSHRL3MBTL1 | |
| SCHEMBL6841912 | 0.89 | RAB9A (0.45) | RAB9ASMN1; SMN2TSHRL3MBTL1LMNA | |
| Hydroxyamine SCHEMBL5794204 | 0.81 | MCL1 (0.46) | MCL1LMNAPPARGPOLB | |
| SCHEMBL5745670 | 0.80 | PPARG (0.52) | RAB9AMCL1SMN1; SMN2TSHRLMNA | |
| Hydroxyamine SCHEMBL5793019 | 0.74 | MCL1 (0.51) | MCL1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL6847480 | 0.73 | PPARG (0.54) | MCL1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL5795383 | 0.73 | MCL1 (0.43) | MCL1SMN1; SMN2TSHRL3MBTL1LMNA | |
| SCHEMBL5746660 | 0.73 | PPARG (0.48) | MCL1TSHRLMNAMAPK1THRB | |
| SCHEMBL5746552 | 0.72 | HIF1A (0.45) | MCL1SMN1; SMN2TSHRLMNATHRB | |
| SCHEMBL5796548 | 0.72 | MCL1 (0.53) | MCL1SMN1; SMN2TSHRL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173427-B1 | HYDROXAMIC ACID DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO (JP) | 2006-04-05 | — | — | EP | disclosed |