Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NCF1 | P14598 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1541573 | 0.90 | LMNA (0.42) | LMNAMAPTCYP2A13SMN1; SMN2HSD17B10 | |
| SCHEMBL111193 | 0.86 | NCF1 (0.57) | LMNAMAPTCYP2A13GAASMN1; SMN2 | |
| SCHEMBL5105938 | 0.84 | KDM1A (0.42) | MAPTCYP2A13GAASMN1; SMN2NCF1 | |
| SCHEMBL10244134 | 0.83 | PKM (0.49) | LMNAMAPTCYP2A13SMN1; SMN2HSD17B10 | |
| SCHEMBL1460361 | 0.83 | LMNA (0.44) | LMNAMAPTGAASMN1; SMN2HSD17B10 | |
| SCHEMBL10558443 | 0.82 | KEAP1 (0.53) | GAANCF1ALDH1A1NPC1KMT2A | |
| SCHEMBL6509065 | 0.80 | PKM (0.60) | LMNAMAPTCYP2A13SMN1; SMN2HSD17B10 | |
| SCHEMBL6703722 | 0.80 | LMNA (0.48) | LMNAMAPTCYP2A13HSD17B10ALDH1A1 | |
| SCHEMBL7008376 | 0.80 | SMN1; SMN2 (0.51) | LMNAMAPTCYP2A13SMN1; SMN2HSD17B10 | |
| SCHEMBL6109462 | 0.79 | HTR1A (0.56) | HSD17B10NCF1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006017406-A1 | CYANOAMIDINE P2X7 ANTAGONISTS FOR THE TREATMENT OF PAIN | ABBOTT LABORATORIES (US) | 2006-02-16 | — | — | WO | disclosed |