SCHEMBL5795382

SCHEMBL5795382

Cc1c(C)n(CCO)c2c(OCCC(C)C)nccc12

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
AAK1 Q2M2I8 1/20 0.35
RAB9A P51151 2/20 0.33
ACSS2 Q9NR19 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.32
PIM1 P11309 1/20 0.31
TTK P33981 1/20 0.31
PIM2 Q9P1W9 1/20 0.31
HTT P42858 1/20 0.31
CYP19A1 P11511 1/20 0.31
DYRK1A Q13627 2/20 0.30
MAPK1 P28482 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5797553 0.99 AAK1 (0.35) AAK1RAB9AACSS2NPC1KMT2A
Hydrochloric Acid SCHEMBL5811037 0.90 ALDH1A1 (0.33) KMT2ADYRK1AMAPK1TDP1
SCHEMBL5810191 0.87 TDP1 (0.33) KMT2AHTTCYP19A1MAPK1TDP1
Hydrochloric Acid SCHEMBL5809596 0.87 KMT2A (0.34) AAK1RAB9ANPC1KMT2ADYRK1A
Hydrochloric Acid SCHEMBL5811743 0.86 TDP1 (0.32) KMT2AHTTCYP19A1TDP1
Hydrochloric Acid SCHEMBL5807412 0.85 ACSS2 (0.34) AAK1ACSS2DYRK1ATDP1
Hydrochloric Acid SCHEMBL5807560 0.85 LMNA (0.32) RAB9AKMT2A
SCHEMBL5810095 0.83 MAPK1 (0.35) AAK1HTTCYP19A1MAPK1TDP1
Hydrochloric Acid SCHEMBL5810379 0.83 TDP1 (0.30) TDP1
SCHEMBL5810118 0.83

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed