SCHEMBL5810191

SCHEMBL5810191

Cc1c(C)n(CC(C)C)c2c(OCCC(C)C)nccc12

nearest known ligand 0.33

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.33
LMNA P02545 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
ALDH1A1 P00352 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
KMT2A Q03164 1/20 0.32
ATM Q13315 1/20 0.32
CDK1 P06493 1/20 0.31
CCNB1 P14635 1/20 0.31
CCNA2 P20248 1/20 0.31
CDK2 P24941 1/20 0.31
CCNA1 P78396 1/20 0.31
HTT P42858 1/20 0.31
CYP19A1 P11511 1/20 0.31
MAPK1 P28482 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5811743 0.99 TDP1 (0.32) TDP1LMNAKDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL5807412 0.90 ACSS2 (0.34) TDP1
Hydrochloric Acid SCHEMBL5811037 0.90 ALDH1A1 (0.33) TDP1LMNAMEN1ALDH1A1MAPT
Hydrochloric Acid SCHEMBL5810379 0.87 TDP1 (0.30) TDP1
SCHEMBL5795382 0.87 AAK1 (0.35) TDP1KMT2AHTTCYP19A1MAPK1
Hydrochloric Acid SCHEMBL5797553 0.86 AAK1 (0.35) KDM4EKMT2AHTTCYP19A1
SCHEMBL5809270 0.86 CYP1A2 (0.31)
Hydrochloric Acid SCHEMBL5809596 0.86 KMT2A (0.34) KDM4EMEN1ALDH1A1POLBKMT2A
SCHEMBL5806831 0.86 MAOA (0.35) TDP1LMNAKDM4EMEN1ALDH1A1
Hydrochloric Acid SCHEMBL5809921 0.85 LMNA (0.32) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2006025717-A1 PYRROLO[2,3-c]PYRIDINE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF YUHAN CORPORATION (KR) 2006-03-09 WO claimed