Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | RXRB | P28702 | 1/20 | 0.36 |
| ▸ | RXRG | P48443 | 1/20 | 0.36 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | PHGDH | O43175 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10946000 | 0.84 | POLB (0.42) | TSHRPOLBFAAHPHGDHMGLL | |
| SCHEMBL5795609 | 0.83 | CFD (0.37) | POLBGAAFAAHPHGDHMGLL | |
| SCHEMBL5797620 | 0.83 | LMNA (0.40) | POLBCYP1A2CYP3A4HTTMEN1 | |
| SCHEMBL2093314 | 0.81 | TSHR (0.47) | TSHRMCOLN3POLBRXRARXRB | |
| SCHEMBL5798051 | 0.78 | FAAH (0.41) | TSHRPOLBCYP1A2GAAFAAH | |
| SCHEMBL2093311 | 0.77 | TSHR (0.42) | TSHRMCOLN3POLBRXRARXRB | |
| SCHEMBL17513418 | 0.77 | FSCN1 (0.53) | TSHRMCOLN3POLBRXRARXRB | |
| SCHEMBL17513254 | 0.76 | TSHR (0.41) | TSHRPOLBRXRARXRBRXRG | |
| SCHEMBL19786 | 0.74 | MAPT (0.46) | TSHRMCOLN3CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL11406875 | 0.73 | GPR142 (0.41) | TSHRPOLBRXRARXRBRXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006037468-A1 | HIV REVERSE TRANSCRIPTASE INHIBITORS | ISTITUTO DI RICERCHE DI BIOLOGIA MOLECOLARE P ANGELETTI SPA (IT) | 2006-04-13 | — | — | WO | claimed |