7-Hydroxyflavanone

7-Hydroxyflavanone

SCHEMBL130266

O=C1CC(c2ccccc2)Oc2cc(O)ccc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 9/20 1.00
CYP19A1 P11511 7/20 1.00
MAOA P21397 1/20 1.00
PSMB5 P28074 1/20 1.00
TUBB4A P04350 1/20 0.86
TUBB P07437 1/20 0.86
YES1 P07947 1/20 0.86
TUBA3C P0DPH7 1/20 0.86
TUBA1B P68363 1/20 0.86
TUBA4A P68366 1/20 0.86
TUBB4B P68371 1/20 0.86
TUBB3 Q13509 1/20 0.86
TUBB2A Q13885 1/20 0.86
TUBB8 Q3ZCM7 1/20 0.86
TUBA3E Q6PEY2 1/20 0.86
TUBA1A Q71U36 1/20 0.86
ESR2 Q92731 1/20 0.86
TUBA1C Q9BQE3 1/20 0.86
TUBB6 Q9BUF5 1/20 0.86
TUBB2B Q9BVA1 1/20 0.86

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
7-Hydroxyflavanone SCHEMBL29843931 1.00 MAOB (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
7-Hydroxyflavanone SCHEMBL126599 1.00 MAOB (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
7-Hydroxyflavanone SCHEMBL1072683 1.00 MAOB (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL3120177 0.93 MAOB (0.87) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL1071066 0.92 CYP19A1 (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL26970367 0.92 CYP19A1 (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL74552 0.92 CYP19A1 (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL29552383 0.92 CYP19A1 (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL30352791 0.92 CYP19A1 (1.00) MAOBCYP19A1MAOAPSMB5TUBB4A
Liquirtigenin SCHEMBL4649862 0.91 CYP19A1 (0.97) MAOBCYP19A1MAOAPSMB5TUBB4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 556 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025091065-A1 FLAVONOID COMPOSITION GRETALS AUSTRALIA PTY LTD (AU) 2025-05-08 WO claimed
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. PONTIFICIA UNIV CATOLICA DE VALPARAISO (CL) 2024-11-14 US claimed
US-20240150797-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES SYMRISE AG (DE) 2024-05-09 US claimed
EP-4301865-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES Symrise AG (DE) 2024-01-10 EP claimed
CN-117242185-A Biocatalytic preparation of dihydrochalcone 西姆莱斯有限公司 2023-12-15 CN claimed
CN-116660543-A Diagnostic and prognostic markers for nonalcoholic fatty liver disease and uses thereof 中国人民解放军陆军军医大学第一附属医院 2023-08-29 CN claimed
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2023-06-08 US claimed
EP-4146194-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS Gretals Australia Pty Ltd (AU) 2023-03-15 EP claimed
WO-2022221968-A1 COMPOSITIONS COMPRISING RESINOUS EXUDATE METABOLITES FROM PLANTS OF THE GENUS ADESMIA, USED TO CONTROL AND TREAT INFECTIONS IN PLANT CROPS; AND METHODS FOR CONTROLLING INFECTIONS IN PLANT CROPS PONTIFICIA UNIVERSIDAD CATÓLICA DE VALPARAÍSO (CL) 2022-10-27 WO claimed
WO-2022184248-A1 BIOCATALYTICAL PRODUCTION OF DIHYDROCHALCONES SYMRISE AG (DE) 2022-09-09 WO claimed
WO-2021222987-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS GRETALS AUSTRALIA PTY LTD (AU) 2021-11-11 WO claimed
US-11040079-B2 Compositions derived from Galenia Africana and methods of use for cancer treatment BIOPHARM NZ LIMITED (NZ) 2021-06-22 US claimed
CN-112716933-A Application of 7-hydroxyflavanone in preparation of medicine for promoting juvenile bone growth 河南省洛阳正骨医院(河南省骨科医院) 2021-04-30 CN claimed
EP-3558333-A1 COMPOSITIONS DERIVED FROMGALENIA AFRICANA Biopharm NZ Limited (NZ) 2019-10-30 EP claimed
WO-2018116146-A1 COMPOSITIONS DERIVED FROM GALENIA AFRICANA AND METHODS OF USE FOR CANCER TREATMENT BIOPHARM NZ LIMITED (NZ) 2018-06-28 WO claimed
US-20110020895-A1 METHODS AND COMPOSITIONS FOR DETERMINING ISOMERASE ENZYMATIC ACTIVITY SALK INSTITUTE FOR BIOLOGICAL STUDIES 2011-01-27 US claimed
US-20080254519-A1 Process for Producing Picolinic Acid Compounds SHINDO KAZUTOSHI 2008-10-16 US claimed
EP-1726645-A1 PROCESS FOR PRODUCING PICOLINIC ACID COMPOUNDS MARINE BIOTECHNOLOGY INSTITUTE CO., LTD. (JP) 2006-11-29 EP claimed
US-20040096955-A1 Methods and compositions for determining isomerase enzymatic activity NATIONAL SCIENCE FOUNDATION 2004-05-20 US claimed
WO-2002018604-A2 METHODS AND COMPOSITIONS FOR DETERMINING ISOMERASE ENZYMATIC ACTIVITY THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) 2002-03-07 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240373850-A1 Compositions comprising resinous exudate metabolites from plants of the genus Adesmia, used to control and treat infections in plant crops; and methods for controlling infections in plant crops. ERG28, RXFP4, CROCC MAOB 2261/4885CYP19A1 2372/4885MAOA 2174/4885
US-20080254519-A1 Process for Producing Picolinic Acid Compounds HPD, PAH, DHPS MAOB 294/4885CYP19A1 126/4885MAOA 187/4885
US-20230172901-A1 COMPOSITIONS AND METHODS FOR THE PROPHYLAXIS AND TREATMENT OF FIBROTIC AND INFLAMMATORY CONDITIONS MMP1, COL1A1, SERPINB1 MAOB 2184/4885CYP19A1 3035/4885MAOA 2155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.