Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | AOC2 | O75106 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5798241 | 1.00 | ALDH1A1 (0.40) | ALDH1A1AOC2MEN1KMT2APOLB | |
| SCHEMBL5798028 | 0.87 | KMT2A (0.43) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5797834 | 0.87 | KMT2A (0.37) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5799304 | 0.87 | KMT2A (0.43) | ALDH1A1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL5820016 | 0.87 | KMT2A (0.37) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5800376 | 0.86 | CYP26A1 (0.40) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL5801142 | 0.86 | CYP26A1 (0.40) | ALDH1A1MEN1KMT2AMAPTRAB9A | |
| SCHEMBL5797762 | 0.83 | EPHX2 (0.41) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5801633 | 0.83 | EPHX2 (0.41) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL5801461 | 0.80 | MAPT (0.37) | ALDH1A1KMT2AMAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006030208-A1 | AMINO ACID | UNIVERSITY OF LEEDS (GB) | 2006-03-23 | — | — | WO | disclosed |