Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 1/20 | 0.38 |
| ▸ | CX3CR1 | P49238 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.37 |
| ▸ | CA1 | P00915 | 5/20 | 0.35 |
| ▸ | CA9 | Q16790 | 5/20 | 0.35 |
| ▸ | CA12 | O43570 | 4/20 | 0.35 |
| ▸ | CA6 | P23280 | 4/20 | 0.35 |
| ▸ | CA5A | P35218 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 4/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 4/20 | 0.35 |
| ▸ | CA4 | P22748 | 3/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9822601 | 0.79 | ALDH1A1 (0.36) | CA2PTGS1PTGS2CES1CYP3A4 | |
| SCHEMBL5353246 | 0.77 | CA1 (0.48) | CXCR2CX3CR1CA2CA1CA9 | |
| SCHEMBL2777012 | 0.76 | PTGS1 (0.42) | CA2PTGS1PTGS2CA1CA12 | |
| SCHEMBL13226856 | 0.76 | CXCR2 (0.46) | CXCR2CX3CR1CA2PTGS1PTGS2 | |
| SCHEMBL29289145 | 0.76 | GLO1 (0.41) | CA2PTGS1PTGS2CA1CA9 | |
| SCHEMBL4440346 | 0.75 | SLC40A1 (0.43) | CXCR2CX3CR1CA2CA1CA9 | |
| SCHEMBL27804376 | 0.73 | CA2 (0.38) | CA2PTGS1PTGS2CA1CA9 | |
| SCHEMBL2929807 | 0.73 | CA2 (0.41) | CA2PTGS1PTGS2CA1CA9 | |
| SCHEMBL947447 | 0.72 | CXCR2 (0.36) | CXCR2CX3CR1CA2PTGS1PTGS2 | |
| SCHEMBL2775322 | 0.72 | PTGS1 (0.42) | CA2PTGS1PTGS2CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006034390-A2 | INHIBITORS OF 15-LIPOXYGENASE | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-03-30 | — | — | WO | disclosed |