SCHEMBL9822601

SCHEMBL9822601

Cc1ccc(Cl)c(Cl)c1S(=O)(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.36
CES1 P23141 1/20 0.35
CYP2C9 P11712 1/20 0.35
CYP3A4 P08684 2/20 0.35
TDP1 Q9NUW8 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.35
TP53 P04637 1/20 0.35
GLA P06280 1/20 0.35
GAA P10253 1/20 0.35
HPGD P15428 1/20 0.35
NT5E P21589 1/20 0.35
CASP1 P29466 1/20 0.35
RECQL P46063 1/20 0.35
CASP7 P55210 1/20 0.35
HSD17B10 Q99714 1/20 0.35
MAPK1 P28482 2/20 0.33
TSHR P16473 1/20 0.33
HTT P42858 1/20 0.33
CDK1 P06493 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27286539 0.85 ALDH1A1 (0.36) ALDH1A1LMNACYP3A4TDP1SMN1; SMN2
SCHEMBL2856393 0.80 ALDH1A1 (0.40) ALDH1A1CYP2C9CYP3A4TDP1SMN1; SMN2
SCHEMBL8375530 0.80 CYP2C9 (0.43) ALDH1A1LMNACES1CYP2C9CYP3A4
SCHEMBL16343725 0.79 ALDH1A1 (0.41) ALDH1A1LMNACYP3A4TDP1SMN1; SMN2
SCHEMBL5798575 0.79 CXCR2 (0.38) LMNACES1CYP2C9CYP3A4PTGS1
SCHEMBL27577874 0.78 CYP2C9 (0.37) ALDH1A1LMNACES1CYP2C9CYP3A4
SCHEMBL1955903 0.77 CYP3A4 (0.50) ALDH1A1LMNACES1CYP2C9CYP3A4
SCHEMBL27657206 0.77 CYP2C9 (0.36) ALDH1A1CES1CYP2C9CYP3A4SMN1; SMN2
SCHEMBL4635992 0.75 SLC40A1 (0.43) ALDH1A1TDP1GAAKDM4EPOLB
SCHEMBL11097853 0.75 ALDH1A1 (0.47) ALDH1A1CYP2C9CYP3A4TDP1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101360705-A Amino-alkyl-amide derivatives as CCR3 receptor ligands SANOFI AVENTIS (FR) 2009-02-04 CN claimed
CN-101360705-A Amino-alkyl-amide derivatives as CCR3 receptor ligands SANOFI AVENTIS (FR) 2009-02-04 CN disclosed
EP-0291588-B1 SIZING AGENT KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1991-09-04 EP disclosed
EP-0224976-B1 METHOD OF SIZING PAPER KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-10-18 EP disclosed
US-4826570-A PARTIAL ESTER OF ALKENYL SUCCINIC ACID, PAPERMAKING KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1989-05-02 US disclosed
EP-0291588-A1 Sizing agent KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1988-11-23 EP disclosed
EP-0224976-A1 Method of sizing paper KABUSHIKI KAISHA CHIYODA KAGAKU KENKYUSHO (JP) 1987-06-10 EP disclosed