Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | RXRA | P19793 | 4/20 | 0.39 |
| ▸ | RXRB | P28702 | 4/20 | 0.39 |
| ▸ | RXRG | P48443 | 3/20 | 0.39 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.36 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10050482 | 0.76 | RXRA (0.49) | MAOBRXRARXRBRXRGPARP10 | |
| SCHEMBL5800790 | 0.74 | HSD17B1 (0.47) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL1480129 | 0.69 | MAPT (0.62) | MAOBMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL1480615 | 0.69 | MAPT (0.58) | MAOBMEN1KMT2AEDNRBEDNRA | |
| SCHEMBL30689245 | 0.67 | PARP10 (0.55) | MAOBPARP10PARP11MEN1KMT2A | |
| SCHEMBL28222642 | 0.66 | KIF11 (0.70) | MAOBRXRARXRBRXRGALDH1A1 | |
| SCHEMBL9171969 | 0.66 | NPC1 (0.66) | MAOBMEN1KMT2ANPC1RAB9A | |
| SCHEMBL25489511 | 0.64 | RXRA (0.48) | MAOBRXRARXRBRXRGALDH1A1 | |
| SCHEMBL15499268 | 0.64 | RXRA (0.48) | MAOBRXRARXRBRXRGALDH1A1 | |
| SCHEMBL2138447 | 0.64 | KIF11 (0.65) | RXRARXRBRXRGALDH1A1CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006060774-A2 | AGENTS THAT INHIBIT FLAVIVIRUS REPLICATION AND USES THEREOF | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) | 2006-06-08 | — | — | WO | disclosed |