Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | HTT | P42858 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | NSD2 | O96028 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.58 |
| ▸ | LGMN | Q99538 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.50 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | PRKDC | P78527 | 2/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20631 | 0.81 | MAPT (0.61) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL4745958 | 0.80 | AKR1C3 (0.69) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| Hydrochloric Acid SCHEMBL16209945 | 0.79 | MAPT (0.65) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL20631313 | 0.79 | LMNA (0.61) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL6992774 | 0.78 | ADRA2C (0.61) | MAPTSMN1; SMN2LMNAHTTLGMN | |
| SCHEMBL224567 | 0.78 | ADRA2C (0.61) | MAPTSMN1; SMN2LMNAHTTLGMN | |
| SCHEMBL30893007 | 0.78 | ALDH1A1 (0.59) | MAPTSMN1; SMN2LMNAHTTKDM4E | |
| SCHEMBL29371026 | 0.78 | ADRA2C (0.61) | MAPTSMN1; SMN2LMNAHTTLGMN | |
| Hydrochloric Acid SCHEMBL14742169 | 0.77 | ADRA2C (0.59) | MAPTSMN1; SMN2LMNAHTTLGMN | |
| SCHEMBL14906622 | 0.76 | MAPT (0.51) | MAPTSMN1; SMN2GAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006025683-A1 | ARYLAMINOMETHYL PROPENYL BENZHYDROXYAMID DERIVATIVES WITH INHIBITORY ACTIVITY AGAINST HISTONE DEACETYLASE AND METHOD FOR THE PREPARATION THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-09 | — | — | WO | disclosed |