Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 7/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.63 |
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | NSD2 | O96028 | 1/20 | 0.63 |
| ▸ | CASP1 | P29466 | 1/20 | 0.63 |
| ▸ | CASP7 | P55210 | 1/20 | 0.63 |
| ▸ | CASP6 | P55212 | 1/20 | 0.63 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.62 |
| ▸ | HTR3A | P46098 | 2/20 | 0.62 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.62 |
| ▸ | HTR3B | O95264 | 1/20 | 0.62 |
| ▸ | HTR5A | P47898 | 1/20 | 0.62 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.62 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 3/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21154120 | 0.87 | MAPT (0.59) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL12806786 | 0.84 | HTR3A (0.72) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL3534699 | 0.82 | HTR3A (0.69) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL29594813 | 0.82 | HTR3A (0.69) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL4649483 | 0.81 | MAPT (0.59) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL17631851 | 0.81 | MAPT (0.59) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL13511022 | 0.81 | MAPT (0.52) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL5798756 | 0.80 | MAPT (0.58) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL4810527 | 0.80 | HTR3A (0.67) | AKR1C3MAPTHTTLMNAKDM4E | |
| SCHEMBL30480097 | 0.80 | HTR3A (0.67) | AKR1C3MAPTHTTLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1147254-A | Prodrugs of morpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 1997-04-09 | — | — | CN | claimed |
| US-12392042-B2 | Alternating current (AC) transition-metal catalysis | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2025-08-19 | — | — | US | disclosed |
| US-20230407492-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2023-12-21 | — | — | US | disclosed |
| EP-4214355-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | Yeda Research and Development Co. Ltd (IL) | 2023-07-26 | — | — | EP | disclosed |
| CN-116113728-A | Alternating Current (AC) transition metal catalysis | 耶达研究与发展有限公司 | 2023-05-12 | — | — | CN | disclosed |
| US-20220144760-A1 | METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND | FUJIFILM CORPORATION (JP) | 2022-05-12 | — | — | US | disclosed |
| WO-2022059010-A1 | ALTERNATING CURRENT (AC) TRANSITION-METAL CATALYSIS | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 2022-03-24 | — | — | WO | disclosed |
| US-9567307-B2 | Amination of aryl alcohol derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-14 | — | — | US | disclosed |
| US-9567307-B2 | Amination of aryl alcohol derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-14 | — | — | US | disclosed |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-31 | — | — | US | disclosed |
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2013-10-31 | — | — | US | disclosed |
| WO-2008098751-A1 | NEW COMPOUNDS WITH ANTIGLUTAMATERGIC PROPERTIES AND USES THEREOF | FAUST PHARMACEUTICALS (FR) | 2008-08-21 | — | — | WO | disclosed |
| CN-1075812-C | Prodrugs of morpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 2001-12-05 | — | — | CN | disclosed |
| US-5817877-A | Metal-catalyzed amination of organic sulfonates to organic amines | YALE UNIVERSITY (US) | 1998-10-06 | — | — | US | disclosed |
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| CN-1147254-A | Prodrugs of morpholine tachykinin receptor antagonists | MERCK & CO INC (US) | 1997-04-09 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130289270-A1 | Amination of Aryl Alcohol Derivatives | SULT2A1, SULT1A1, ADH5 | AKR1C3 348/4885MAPT 3931/4885HTT 2342/4885 |
| US-20220144760-A1 | METHOD OF PRODUCING CARBONYL COMPOUND AND FLOW TYPE REACTION SYSTEM OF PRODUCING CARBONYL COMPOUND | NOXO1, MT-CO2, MT-ATP8 | AKR1C3 515/4885MAPT 2763/4885HTT 2499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.